C2AL: Cohort-Contrastive Auxiliary Learning for Large-scale Recommendation Systems

Training large-scale recommendation models under a single global objective implicitly assumes homogeneity across user populations. However, real-world data are composites of heterogeneous cohorts with distinct conditional distributions. As models increase in scale and complexity and as more data is used for training, they become dominated by central distribution patterns, neglecting head and tail regions. This imbalance limits the model's learning ability and can result in inactive attention weights or dead neurons. In this paper, we reveal how the attention mechanism can play a key role in factorization machines for shared embedding selection, and propose to address this challenge by analyzing the substructures in the dataset and exposing those with strong distributional contrast through auxiliary learning. Unlike previous research, which heuristically applies weighted labels or multi-task heads to mitigate such biases, we leverage partially conflicting auxiliary labels to regularize the shared representation. This approach customizes the learning process of attention layers to preserve mutual information with minority cohorts while improving global performance. We evaluated C2AL on massive production datasets with billions of data points each for six SOTA models. Experiments show that the factorization machine is able to capture fine-grained user-ad interactions using the proposed method, achieving up to a 0.16% reduction in normalized entropy overall and delivering gains exceeding 0.30% on targeted minority cohorts.

Automated Characterization of Stenosis in Invasive Coronary Angiography Images with Convolutional Neural Networks

The determination of a coronary stenosis and its severity in current clinical workflow is typically accomplished manually via physician visual assessment (PVA) during invasive coronary angiography. While PVA has shown large inter-rater variability, the more reliable and accurate alternative of Quantitative Coronary Angiography (QCA) is challenging to perform in real-time due to the busy workflow in cardiac catheterization laboratories. We propose a deep learning approach based on Convolutional Neural Networks (CNN) that automatically characterizes and analyzes coronary stenoses in real-time by automating clinical tasks performed during QCA. Our deep learning methods for localization, segmentation and classification of stenosis in still-frame invasive coronary angiography (ICA) images of the right coronary artery (RCA) achieve performance of 72.7% localization accuracy, 0.704 dice coefficient and 0.825 C-statistic in each respective task. Integrated in an end-to-end approach, our model's performance shows statistically significant improvement in false discovery rate over the current standard in real-time clinical stenosis assessment, PVA. To the best of the authors' knowledge, this is the first time an automated machine learning system has been developed that can implement tasks performed in QCA, and the first time an automated machine learning system has demonstrated significant improvement over the current clinical standard for rapid RCA stenosis analysis.