3D object detection is vital as it would enable us to capture objects' sizes, orientation, and position in the world. As a result, we would be able to use this 3D detection in real-world applications such as Augmented Reality (AR), self-driving cars, and robotics which perceive the world the same way we do as humans. Monocular 3D Object Detection is the task to draw 3D bounding box around objects in a single 2D RGB image. It is localization task but without any extra information like depth or other sensors or multiple images. Monocular 3D object detection is an important yet challenging task. Beyond the significant progress in image-based 2D object detection, 3D understanding of real-world objects is an open challenge that has not been explored extensively thus far. In addition to the most closely related studies.
High-dimensional biomarkers such as genomics are increasingly being measured in randomized clinical trials. Consequently, there is a growing interest in developing methods that improve the power to detect biomarker-treatment interactions. We adapt recently proposed two-stage interaction detecting procedures in the setting of randomized clinical trials. We also propose a new stage 1 multivariate screening strategy using ridge regression to account for correlations among biomarkers. For this multivariate screening, we prove the asymptotic between-stage independence, required for the family-wise error rate control, under the biomarker-treatment independence. Simulation results show that in various scenarios, the ridge regression screening procedure can provide substantially greater power than the traditional one-biomarker-at-a-time screening procedure in highly correlated data. We also exemplify our approach in two real clinical trial data applications.