Cardiac MRI Semantic Segmentation for Ventricles and Myocardium using Deep Learning

Automated noninvasive cardiac diagnosis plays a critical role in the early detection of cardiac disorders and cost-effective clinical management. Automated diagnosis involves the automated segmentation and analysis of cardiac images. Precise delineation of cardiac substructures and extraction of their morphological attributes are essential for evaluating the cardiac function, and diagnosing cardiovascular disease such as cardiomyopathy, valvular diseases, abnormalities related to septum perforations, and blood-flow rate. Semantic segmentation labels the CMR image at the pixel level, and localizes its subcomponents to facilitate the detection of abnormalities, including abnormalities in cardiac wall motion in an aging heart with muscle abnormalities, vascular abnormalities, and valvular abnormalities. In this paper, we describe a model to improve semantic segmentation of CMR images. The model extracts edge-attributes and context information during down-sampling of the U-Net and infuses this information during up-sampling to localize three major cardiac structures: left ventricle cavity (LV); right ventricle cavity (RV); and LV myocardium (LMyo). We present an algorithm and performance results. A comparison of our model with previous leading models, using similarity metrics between actual image and segmented image, shows that our approach improves Dice similarity coefficient (DSC) by 2%-11% and lowers Hausdorff distance (HD) by 1.6 to 5.7 mm.

DADU: Dual Attention-based Deep Supervised UNet for Automated Semantic Segmentation of Cardiac Images

We propose an enhanced deep learning-based model for image segmentation of the left and right ventricles and myocardium scar tissue from cardiac magnetic resonance (CMR) images. The proposed technique integrates UNet, channel and spatial attention, edge-detection based skip-connection and deep supervised learning to improve the accuracy of the CMR image-segmentation. Images are processed using multiple channels to generate multiple feature-maps. We built a dual attention-based model to integrate channel and spatial attention. The use of extracted edges in skip connection improves the reconstructed images from feature-maps. The use of deep supervision reduces vanishing gradient problems inherent in classification based on deep neural networks. The algorithms for dual attention-based model, corresponding implementation and performance results are described. The performance results show that this approach has attained high accuracy: 98% Dice Similarity Score (DSC) and significantly lower Hausdorff Distance (HD). The performance results outperform other leading techniques both in DSC and HD.

Multi-Layer Feature Fusion with Cross-Channel Attention-Based U-Net for Kidney Tumor Segmentation

Renal tumors, especially renal cell carcinoma (RCC), show significant heterogeneity, posing challenges for diagnosis using radiology images such as MRI, echocardiograms, and CT scans. U-Net based deep learning techniques are emerging as a promising approach for automated medical image segmentation for minimally invasive diagnosis of renal tumors. However, current techniques need further improvements in accuracy to become clinically useful to radiologists. In this study, we present an improved U-Net based model for end-to-end automated semantic segmentation of CT scan images to identify renal tumors. The model uses residual connections across convolution layers, integrates a multi-layer feature fusion (MFF) and cross-channel attention (CCA) within encoder blocks, and incorporates skip connections augmented with additional information derived using MFF and CCA. We evaluated our model on the KiTS19 dataset, which contains data from 210 patients. For kidney segmentation, our model achieves a Dice Similarity Coefficient (DSC) of 0.97 and a Jaccard index (JI) of 0.95. For renal tumor segmentation, our model achieves a DSC of 0.96 and a JI of 0.91. Based on a comparison of available DSC scores, our model outperforms the current leading models.