Abstract:This paper introduces $π$-RAG, a novel architecture for oblivious retrieval that decouples Large Language Models (LLMs) from sensitive data storage without sacrificing semantic understanding. Traditional Retrieval-Augmented Generation (RAG) architectures expose raw vector embeddings to potential inversion attacks and nondeterministic retrieval failures. To address this, we utilize the digits of $π$ as a source of transcendental entropy, creating an immutable indirection layer between the LLM and private records. The value $π$ provides immutability, is uneditable and math governs it. The architecture also introduces a Semantic Quantization Layer. This layer projects user inputs onto a pre-computed manifold of Canonical Intent Centroids. RAG performs vector cosine similarity but here it maps the centroids to deterministic offsets via cryptographic salt. The resulting $π$-key is a pointer to standardized payload from the actual datastore. By replacing direct access to the datastore via LLM with this transcendental layer, $π$-RAG mathematically guarantees that the inference remains oblivious to the data. This architecture unifies deterministic randomness, auditability, and differential privacy, demonstrating high efficacy for high-compliance sectors such as finance and healthcare.
Abstract:Global health surveillance is currently facing a challenge of Knowledge Gaps. While general-purpose AI has proliferated, it remains fundamentally unsuited for the high-stakes epidemiological domain due to chronic hallucinations and an inability to navigate specialized data silos. This paper introduces ARIES (Agentic Retrieval Intelligence for Epidemiological Surveillance), a specialized, autonomous multi-agent framework designed to move beyond static, disease-specific dashboards toward a dynamic intelligence ecosystem. Built on a hierarchical command structure, ARIES utilizes GPTs to orchestrate a scalable swarm of sub-agents capable of autonomously querying World Health Organization (WHO), Center for Disease Control and Prevention (CDC), and peer-reviewed research papers. By automating the extraction and logical synthesis of surveillance data, ARIES provides a specialized reasoning that identifies emergent threats and signal divergence in near real-time. This modular architecture proves that a task-specific agentic swarm can outperform generic models, offering a robust, extensible for next-generation outbreak response and global health intelligence.