Utilizing AI and Social Media Analytics to Discover Adverse Side Effects of GLP-1 Receptor Agonists

Adverse side effects (ASEs) of drugs, revealed after FDA approval, pose a threat to patient safety. To promptly detect overlooked ASEs, we developed a digital health methodology capable of analyzing massive public data from social media, published clinical research, manufacturers' reports, and ChatGPT. We uncovered ASEs associated with the glucagon-like peptide 1 receptor agonists (GLP-1 RA), a market expected to grow exponentially to $133.5 billion USD by 2030. Using a Named Entity Recognition (NER) model, our method successfully detected 21 potential ASEs overlooked upon FDA approval, including irritability and numbness. Our data-analytic approach revolutionizes the detection of unreported ASEs associated with newly deployed drugs, leveraging cutting-edge AI-driven social media analytics. It can increase the safety of new drugs in the marketplace by unlocking the power of social media to support regulators and manufacturers in the rapid discovery of hidden ASE risks.

Using Online Customer Reviews to Classify, Predict, and Learn about Domestic Robot Failures

There is a knowledge gap regarding which types of failures robots undergo in domestic settings and how these failures influence customer experience. We classified 10,072 customer reviews of small utilitarian domestic robots on Amazon by the robotic failures described in them, grouping failures into twelve types and three categories (Technical, Interaction, and Service). We identified sources and types of failures previously overlooked in the literature, combining them into an updated failure taxonomy. We analyzed their frequencies and relations to customer star ratings. Results indicate that for utilitarian domestic robots, Technical failures were more detrimental to customer experience than Interaction or Service failures. Issues with Task Completion and Robustness & Resilience were commonly reported and had the most significant negative impact. Future failure-prevention and response strategies should address the technical ability of the robot to meet functional goals, operate and maintain structural integrity over time. Usability and interaction design were less detrimental to customer experience, indicating that customers may be more forgiving of failures that impact these aspects for the robots and practical uses examined. Further, we developed a Natural Language Processing model capable of predicting whether a customer review contains content that describes a failure and the type of failure it describes. With this knowledge, designers and researchers of robotic systems can prioritize design and development efforts towards essential issues.