A Role-Based LLM Framework for Structured Information Extraction from Healthy Food Policies

Current Large Language Model (LLM) approaches for information extraction (IE) in the healthy food policy domain are often hindered by various factors, including misinformation, specifically hallucinations, misclassifications, and omissions that result from the structural diversity and inconsistency of policy documents. To address these limitations, this study proposes a role-based LLM framework that automates the IE from unstructured policy data by assigning specialized roles: an LLM policy analyst for metadata and mechanism classification, an LLM legal strategy specialist for identifying complex legal approaches, and an LLM food system expert for categorizing food system stages. This framework mimics expert analysis workflows by incorporating structured domain knowledge, including explicit definitions of legal mechanisms and classification criteria, into role-specific prompts. We evaluate the framework using 608 healthy food policies from the Healthy Food Policy Project (HFPP) database, comparing its performance against zero-shot, few-shot, and chain-of-thought (CoT) baselines using Llama-3.3-70B. Our proposed framework demonstrates superior performance in complex reasoning tasks, offering a reliable and transparent methodology for automating IE from health policies.

NED-Tree: Bridging the Semantic Gap with Nonlinear Element Decomposition Tree for LLM Nonlinear Optimization Modeling

Automating the translation of Operations Research (OR) problems from natural language to executable models is a critical challenge. While Large Language Models (LLMs) have shown promise in linear tasks, they suffer from severe performance degradation in real-world nonlinear scenarios due to semantic misalignment between mathematical formulations and solver codes, as well as unstable information extraction. In this study, we introduce NED-Tree, a systematic framework designed to bridge the semantic gap. NED-Tree employs (a) a sentence-by-sentence extraction strategy to ensure robust parameter mapping and traceability; and (b) a recursive tree-based structure that adaptively decomposes complex nonlinear terms into solver-compatible sub-elements. Additionally, we present NEXTOR, a novel benchmark specifically designed for complex nonlinear, extensive-constraint OR problems. Experiments across 10 benchmarks demonstrate that NED-Tree establishes a new state-of-the-art with 72.51% average accuracy, NED-Tree is the first framework that drives LLMs to resolve nonlinear modeling difficulties through element decomposition, achieving alignment between modeling semantics and code semantics. The NED-Tree framework and benchmark are accessible in the anonymous repository https://anonymous.4open.science/r/NORA-NEXTOR.

Development and multi-center evaluation of domain-adapted speech recognition for human-AI teaming in real-world gastrointestinal endoscopy

Automatic speech recognition (ASR) is a critical interface for human-AI interaction in gastrointestinal endoscopy, yet its reliability in real-world clinical settings is limited by domain-specific terminology and complex acoustic conditions. Here, we present EndoASR, a domain-adapted ASR system designed for real-time deployment in endoscopic workflows. We develop a two-stage adaptation strategy based on synthetic endoscopy reports, targeting domain-specific language modeling and noise robustness. In retrospective evaluation across six endoscopists, EndoASR substantially improves both transcription accuracy and clinical usability, reducing character error rate (CER) from 20.52% to 14.14% and increasing medical term accuracy (Med ACC) from 54.30% to 87.59%. In a prospective multi-center study spanning five independent endoscopy centers, EndoASR demonstrates consistent generalization under heterogeneous real-world conditions. Compared with the baseline Paraformer model, CER is reduced from 16.20% to 14.97%, while Med ACC is improved from 61.63% to 84.16%, confirming its robustness in practical deployment scenarios. Notably, EndoASR achieves a real-time factor (RTF) of 0.005, significantly faster than Whisper-large-v3 (RTF 0.055), while maintaining a compact model size of 220M parameters, enabling efficient edge deployment. Furthermore, integration with large language models demonstrates that improved ASR quality directly enhances downstream structured information extraction and clinician-AI interaction. These results demonstrate that domain-adapted ASR can serve as a reliable interface for human-AI teaming in gastrointestinal endoscopy, with consistent performance validated across multi-center real-world clinical settings.

GroundVTS: Visual Token Sampling in Multimodal Large Language Models for Video Temporal Grounding

Video temporal grounding (VTG) is a critical task in video understanding and a key capability for extending video large language models (Vid-LLMs) to broader applications. However, existing Vid-LLMs rely on uniform frame sampling to extract video information, resulting in a sparse distribution of key frames and the loss of crucial temporal cues. To address this limitation, we propose Grounded Visual Token Sampling (GroundVTS), a Vid-LLM architecture that focuses on the most informative temporal segments. GroundVTS employs a fine-grained, query-guided mechanism to filter visual tokens before feeding them into the LLM, thereby preserving essential spatio-temporal information and maintaining temporal coherence. Futhermore, we introduce a progressive optimization strategy that enables the LLM to effectively adapt to the non-uniform distribution of visual features, enhancing its ability to model temporal dependencies and achieve precise video localization. We comprehensively evaluate GroundVTS on three standard VTG benchmarks, where it outperforms existing methods, achieving a 7.7-point improvement in mIoU for moment retrieval and 12.0-point improvement in mAP for highlight detection. Code is available at https://github.com/Florence365/GroundVTS.

Four Generations of Quantum Biomedical Sensors

Quantum sensing technologies offer transformative potential for ultra-sensitive biomedical sensing, yet their clinical translation remains constrained by classical noise limits and a reliance on macroscopic ensembles. We propose a unifying generational framework to organize the evolving landscape of quantum biosensors based on their utilization of quantum resources. First-generation devices utilize discrete energy levels for signal transduction but follow classical scaling laws. Second-generation sensors exploit quantum coherence to reach the standard quantum limit, while third-generation architectures leverage entanglement and spin squeezing to approach Heisenberg-limited precision. We further define an emerging fourth generation characterized by the end-to-end integration of quantum sensing with quantum learning and variational circuits, enabling adaptive inference directly within the quantum domain. By analyzing critical parameters such as bandwidth matching and sensor-tissue proximity, we identify key technological bottlenecks and propose a roadmap for transitioning from measuring physical observables to extracting structured biological information with quantum-enhanced intelligence.

TOL: Textual Localization with OpenStreetMap

Natural language provides an intuitive way to express spatial intent in geospatial applications. While existing localization methods often rely on dense point cloud maps or high-resolution imagery, OpenStreetMap (OSM) offers a compact and freely available map representation that encodes rich semantic and structural information, making it well suited for large-scale localization. However, text-to-OSM (T2O) localization remains largely unexplored. In this paper, we formulate the T2O global localization task, which aims to estimate accurate 2 degree-of-freedom (DoF) positions in urban environments from textual scene descriptions without relying on geometric observations or GNSS-based initial location. To support the proposed task, we introduce TOL, a large-scale benchmark spanning multiple continents and diverse urban environments. TOL contains approximately 121K textual queries paired with OSM map tiles and covers about 316 km of road trajectories across Boston, Karlsruhe, and Singapore. We further propose TOLoc, a coarse-to-fine localization framework that explicitly models the semantics of surrounding objects and their directional information. In the coarse stage, direction-aware features are extracted from both textual descriptions and OSM tiles to construct global descriptors, which are used to retrieve candidate locations for the query. In the fine stage, the query text and top-1 retrieved tile are jointly processed, where a dedicated alignment module fuses textual descriptor and local map features to regress the 2-DoF pose. Experimental results demonstrate that TOLoc achieves strong localization performance, outperforming the best existing method by 6.53%, 9.93%, and 8.31% at 5m, 10m, and 25m thresholds, respectively, and shows strong generalization to unseen environments. Dataset, code and models will be publicly available at: https://github.com/WHU-USI3DV/TOL.

A deep learning pipeline for PAM50 subtype classification using histopathology images and multi-objective patch selection

Breast cancer is a highly heterogeneous disease with diverse molecular profiles. The PAM50 gene signature is widely recognized as a standard for classifying breast cancer into intrinsic subtypes, enabling more personalized treatment strategies. In this study, we introduce a novel optimization-driven deep learning framework that aims to reduce reliance on costly molecular assays by directly predicting PAM50 subtypes from H&E-stained whole-slide images (WSIs). Our method jointly optimizes patch informativeness, spatial diversity, uncertainty, and patch count by combining the non-dominated sorting genetic algorithm II (NSGA-II) with Monte Carlo dropout-based uncertainty estimation. The proposed method can identify a small but highly informative patch subset for classification. We used a ResNet18 backbone for feature extraction and a custom CNN head for classification. For evaluation, we used the internal TCGA-BRCA dataset as the training cohort and the external CPTAC-BRCA dataset as the test cohort. On the internal dataset, an F1-score of 0.8812 and an AUC of 0.9841 using 627 WSIs from the TCGA-BRCA cohort were achieved. The performance of the proposed approach on the external validation dataset showed an F1-score of 0.7952 and an AUC of 0.9512. These findings indicate that the proposed optimization-guided, uncertainty-aware patch selection can achieve high performance and improve the computational efficiency of histopathology-based PAM50 classification compared to existing methods, suggesting a scalable imaging-based replacement that has the potential to support clinical decision-making.

Hidden Meanings in Plain Sight: RebusBench for Evaluating Cognitive Visual Reasoning

Large Vision-Language Models (LVLMs) have achieved remarkable proficiency in explicit visual recognition, effectively describing what is directly visible in an image. However, a critical cognitive gap emerges when the visual input serves only as a clue rather than the answer. We identify that current models struggle with the complex, multi-step reasoning required to solve problems where information is not explicitly depicted. Successfully solving a rebus puzzle requires a distinct cognitive workflow: the model must extract visual and textual attributes, retrieve linguistic prior knowledge (such as idioms), and perform abstract mapping to synthesize these elements into a meaning that exists outside the pixel space. To evaluate this neurosymbolic capability, we introduce RebusBench, a benchmark of 1,164 puzzles designed to test this specific integration of perception and knowledge. Our evaluation of state-of-the-art models (including Qwen, InternVL, and LLaVA) shows a severe deficiency: performance saturates below 10% Exact Match and 20% semantic accuracy, with no significant improvement observed from model scaling or In-Context Learning (ICL). These findings suggest that while models possess the necessary visual and linguistic components, they lack the cognitive reasoning glue to connect them. Project page available at https://amirkasaei.com/rebusbench/.

What Do Claim Verification Datasets Actually Test? A Reasoning Trace Analysis

Despite rapid progress in claim verification, we lack a systematic understanding of what reasoning these benchmarks actually exercise. We generate structured reasoning traces for 24K claim-verification examples across 9 datasets using GPT-4o-mini and find that direct evidence extraction dominates, while multi-sentence synthesis and numerical reasoning are severely under-represented. A dataset-level breakdown reveals stark biases: some datasets almost exclusively test lexical matching, while others require information synthesis in roughly half of cases. Using a compact 1B-parameter reasoning verifier, we further characterize five error types and show that error profiles vary dramatically by domain -- general-domain verification is dominated by lexical overlap bias, scientific verification by overcautiousness, and mathematical verification by arithmetic reasoning failures. Our findings suggest that high benchmark scores primarily reflect retrieval-plus-entailment ability. We outline recommendations for building more challenging evaluation suites that better test the reasoning capabilities verification systems need.

AfrIFact: Cultural Information Retrieval, Evidence Extraction and Fact Checking for African Languages

Assessing the veracity of a claim made online is a complex and important task with real-world implications. When these claims are directed at communities with limited access to information and the content concerns issues such as healthcare and culture, the consequences intensify, especially in low-resource languages. In this work, we introduce AfrIFact, a dataset that covers the necessary steps for automatic fact-checking (i.e., information retrieval, evidence extraction, and fact checking), in ten African languages and English. Our evaluation results show that even the best embedding models lack cross-lingual retrieval capabilities, and that cultural and news documents are easier to retrieve than healthcare-domain documents, both in large corpora and in single documents. We show that LLMs lack robust multilingual fact-verification capabilities in African languages, while few-shot prompting improves performance by up to 43% in AfriqueQwen-14B, and task-specific fine-tuning further improves fact-checking accuracy by up to 26%. These findings, along with our release of the AfrIFact dataset, encourage work on low-resource information retrieval, evidence retrieval, and fact checking.