Thin-cap fibroatheroma (TCFA) is a prominent risk factor for plaque rupture. Intravascular optical coherence tomography (IVOCT) enables identification of fibrous cap (FC), measurement of FC thicknesses, and assessment of plaque vulnerability. We developed a fully-automated deep learning method for FC segmentation. This study included 32,531 images across 227 pullbacks from two registries. Images were semi-automatically labeled using our OCTOPUS with expert editing using established guidelines. We employed preprocessing including guidewire shadow detection, lumen segmentation, pixel-shifting, and Gaussian filtering on raw IVOCT (r,theta) images. Data were augmented in a natural way by changing theta in spiral acquisitions and by changing intensity and noise values. We used a modified SegResNet and comparison networks to segment FCs. We employed transfer learning from our existing much larger, fully-labeled calcification IVOCT dataset to reduce deep-learning training. Overall, our method consistently delivered better FC segmentation results (Dice: 0.837+/-0.012) than other deep-learning methods. Transfer learning reduced training time by 84% and reduced the need for more training samples. Our method showed a high level of generalizability, evidenced by highly-consistent segmentations across five-fold cross-validation (sensitivity: 85.0+/-0.3%, Dice: 0.846+/-0.011) and the held-out test (sensitivity: 84.9%, Dice: 0.816) sets. In addition, we found excellent agreement of FC thickness with ground truth (2.95+/-20.73 um), giving clinically insignificant bias. There was excellent reproducibility in pre- and post-stenting pullbacks (average FC angle: 200.9+/-128.0 deg / 202.0+/-121.1 deg). Our method will be useful for multiple research purposes and potentially for planning stent deployments that avoid placing a stent edge over an FC.
Deep generative models are promising in detecting novel cyber-physical attacks, mitigating the vulnerability of Cyber-physical systems (CPSs) without relying on labeled information. Nonetheless, these generative models face challenges in identifying attack behaviors that closely resemble normal data, or deviate from the normal data distribution but are in close proximity to the manifold of the normal cluster in latent space. To tackle this problem, this article proposes a novel unsupervised dual variational generative adversarial model named MST-DVGAN, to perform anomaly detection in multivariate time series data for CPS security. The central concept is to enhance the model's discriminative capability by widening the distinction between reconstructed abnormal samples and their normal counterparts. Specifically, we propose an augmented module by imposing contrastive constraints on the reconstruction process to obtain a more compact embedding. Then, by exploiting the distribution property and modeling the normal patterns of multivariate time series, a variational autoencoder is introduced to force the generative adversarial network (GAN) to generate diverse samples. Furthermore, two augmented loss functions are designed to extract essential characteristics in a self-supervised manner through mutual guidance between the augmented samples and original samples. Finally, a specific feature center loss is introduced for the generator network to enhance its stability. Empirical experiments are conducted on three public datasets, namely SWAT, WADI and NSL_KDD. Comparing with the state-of-the-art methods, the evaluation results show that the proposed MTS-DVGAN is more stable and can achieve consistent performance improvement.
The best encoding is the one that is interpretable in nature. In this work, we introduce a novel model that incorporates an interpretable bottleneck-termed the Filter Bank (FB)-at the outset of a Variational Autoencoder (VAE). This arrangement compels the VAE to attend on the most informative segments of the input signal, fostering the learning of a novel encoding ${f_0}$ which boasts enhanced interpretability and clusterability over traditional latent spaces. By deliberately constraining the VAE with this FB, we intentionally constrict its capacity to access broad input domain information, promoting the development of an encoding that is discernible, separable, and of reduced dimensionality. The evolutionary learning trajectory of ${f_0}$ further manifests as a dynamic hierarchical tree, offering profound insights into cluster similarities. Additionally, for handling intricate data configurations, we propose a tailored decoder structure that is symmetrically aligned with FB's architecture. Empirical evaluations highlight the superior efficacy of ISVAE, which compares favorably to state-of-the-art results in clustering metrics across real-world datasets.
Computed Tomography (CT) with its remarkable capability for three-dimensional imaging from multiple projections, enjoys a broad range of applications in clinical diagnosis, scientific observation, and industrial detection. Neural Adaptive Tomography (NeAT) is a recently proposed 3D rendering method based on neural radiance field for CT, and it demonstrates superior performance compared to traditional methods. However, it still faces challenges when dealing with the substantial perturbations and pose shifts encountered in CT scanning processes. Here, we propose a neural rendering method for CT reconstruction, named Iterative Neural Adaptive Tomography (INeAT), which incorporates iterative posture optimization to effectively counteract the influence of posture perturbations in data, particularly in cases involving significant posture variations. Through the implementation of a posture feedback optimization strategy, INeAT iteratively refines the posture corresponding to the input images based on the reconstructed 3D volume. We demonstrate that INeAT achieves artifact-suppressed and resolution-enhanced reconstruction in scenarios with significant pose disturbances. Furthermore, we show that our INeAT maintains comparable reconstruction performance to stable-state acquisitions even using data from unstable-state acquisitions, which significantly reduces the time required for CT scanning and relaxes the stringent requirements on imaging hardware systems, underscoring its immense potential for applications in short-time and low-cost CT technology.
Hierarchical federated learning (HFL) shows great advantages over conventional two-layer federated learning (FL) in reducing network overhead and interaction latency while still retaining the data privacy of distributed FL clients. However, the communication and energy overhead still pose a bottleneck for HFL performance, especially as the number of clients raises dramatically. To tackle this issue, we propose a non-orthogonal multiple access (NOMA) enabled HFL system under semi-synchronous cloud model aggregation in this paper, aiming to minimize the total cost of time and energy at each HFL global round. Specifically, we first propose a novel fuzzy logic based client orchestration policy considering client heterogenerity in multiple aspects, including channel quality, data quantity and model staleness. Subsequently, given the fuzzy based client-edge association, a joint edge server scheduling and resource allocation problem is formulated. Utilizing problem decomposition, we firstly derive the closed-form solution for the edge server scheduling subproblem via the penalty dual decomposition (PDD) method. Next, a deep deterministic policy gradient (DDPG) based algorithm is proposed to tackle the resource allocation subproblem considering time-varying environments. Finally, extensive simulations demonstrate that the proposed scheme outperforms the considered benchmarks regarding HFL performance improvement and total cost reduction.
This study proposes a new approach that investigates differences in topological characteristics of visual networks, which are constructed using fMRI BOLD time-series corresponding to visual datasets of COCO, ImageNet, and SUN. A publicly available BOLD5000 dataset is utilized that contains fMRI scans while viewing 5254 images of diverse complexities. The objective of this study is to examine how network topology differs in response to distinct visual stimuli from these visual datasets. To achieve this, 0- and 1-dimensional persistence diagrams are computed for each visual network representing COCO, ImageNet, and SUN. For extracting suitable features from topological persistence diagrams, K-means clustering is executed. The extracted K-means cluster features are fed to a novel deep-hybrid model that yields accuracy in the range of 90%-95% in classifying these visual networks. To understand vision, this type of visual network categorization across visual datasets is important as it captures differences in BOLD signals while perceiving images with different contexts and complexities. Furthermore, distinctive topological patterns of visual network associated with each dataset, as revealed from this study, could potentially lead to the development of future neuroimaging biomarkers for diagnosing visual processing disorders like visual agnosia or prosopagnosia, and tracking changes in visual cognition over time.
4D panoptic segmentation is a challenging but practically useful task that requires every point in a LiDAR point-cloud sequence to be assigned a semantic class label, and individual objects to be segmented and tracked over time. Existing approaches utilize only LiDAR inputs which convey limited information in regions with point sparsity. This problem can, however, be mitigated by utilizing RGB camera images which offer appearance-based information that can reinforce the geometry-based LiDAR features. Motivated by this, we propose 4D-Former: a novel method for 4D panoptic segmentation which leverages both LiDAR and image modalities, and predicts semantic masks as well as temporally consistent object masks for the input point-cloud sequence. We encode semantic classes and objects using a set of concise queries which absorb feature information from both data modalities. Additionally, we propose a learned mechanism to associate object tracks over time which reasons over both appearance and spatial location. We apply 4D-Former to the nuScenes and SemanticKITTI datasets where it achieves state-of-the-art results.
Learning new tasks accumulatively without forgetting remains a critical challenge in continual learning. Generative experience replay addresses this challenge by synthesizing pseudo-data points for past learned tasks and later replaying them for concurrent training along with the new tasks' data. Generative replay is the best strategy for continual learning under a strict class-incremental setting when certain constraints need to be met: (i) constant model size, (ii) no pre-training dataset, and (iii) no memory buffer for storing past tasks' data. Inspired by the biological nervous system mechanisms, we introduce a time-aware regularization method to dynamically fine-tune the three training objective terms used for generative replay: supervised learning, latent regularization, and data reconstruction. Experimental results on major benchmarks indicate that our method pushes the limit of brain-inspired continual learners under such strict settings, improves memory retention, and increases the average performance over continually arriving tasks.
The tracking and imaging of high-speed moving objects hold significant promise for application in various fields. Single-pixel imaging enables the progressive capture of a fast-moving translational object through motion compensation. However, achieving a balance between a short reconstruction time and a good image quality is challenging. In this study, we present a approach that simultaneously incorporates position encoding and spatial information encoding through the Fourier patterns. The utilization of Fourier patterns with specific spatial frequencies ensures robust and accurate object localization. By exploiting the properties of the Fourier transform, our method achieves a remarkable reduction in time complexity and memory consumption while significantly enhancing image quality. Furthermore, we introduce an optimized sampling strategy specifically tailored for small moving objects, significantly reducing the required dwell time for imaging. The proposed method provides a practical solution for the real-time tracking, imaging and edge detection of translational objects, underscoring its considerable potential for diverse applications.
Conversational agents participating in multi-party interactions face significant challenges in dialogue state tracking, since the identity of the speaker adds significant contextual meaning. It is common to utilise diarisation models to identify the speaker. However, it is not clear if these are accurate enough to correctly identify specific conversational events such as agreement or disagreement during a real-time interaction. This study uses a cooperative quiz, where the conversational agent acts as quiz-show host, to determine whether diarisation or a frequency-and-proximity-based method is more accurate at determining agreement, and whether this translates to feelings of engagement from the players. Experimental results show that our procedural system was more engaging to players, and was more accurate at detecting agreement, reaching an average accuracy of 0.44 compared to 0.28 for the diarised system.