Automatic CT segmentation of proximal femur is crucial for the diagnosis and risk stratification of orthopedic diseases; however, current methods for the femur CT segmentation mainly rely on manual interactive segmentation, which is time-consuming and has limitations in both accuracy and reproducibility. In this study, we proposed an approach based on deep learning for the automatic extraction of the periosteal and endosteal contours of proximal femur in order to differentiate cortical and trabecular bone compartments. A three-dimensional (3D) end-to-end fully convolutional neural network, which can better combine the information between neighbor slices and get more accurate segmentation results, was developed for our segmentation task. 100 subjects aged from 50 to 87 years with 24,399 slices of proximal femur CT images were enrolled in this study. The separation of cortical and trabecular bone derived from the QCT software MIAF-Femur was used as the segmentation reference. We randomly divided the whole dataset into a training set with 85 subjects for 10-fold cross-validation and a test set with 15 subjects for evaluating the performance of models. Two models with the same network structures were trained and they achieved a dice similarity coefficient (DSC) of 97.87% and 96.49% for the periosteal and endosteal contours, respectively. To verify the excellent performance of our model for femoral segmentation, we measured the volume of different parts of the femur and compared it with the ground truth and the relative errors between predicted result and ground truth are all less than 5%. It demonstrated a strong potential for clinical use, including the hip fracture risk prediction and finite element analysis.
Digital Twin was introduced over a decade ago, as an innovative all-encompassing tool, with perceived benefits including real-time monitoring, simulation and forecasting. However, the theoretical framework and practical implementations of digital twins (DT) are still far from this vision. Although successful implementations exist, sufficient implementation details are not publicly available, therefore it is difficult to assess their effectiveness, draw comparisons and jointly advance the DT methodology. This work explores the various DT features and current approaches, the shortcomings and reasons behind the delay in the implementation and adoption of digital twin. Advancements in machine learning, internet of things and big data have contributed hugely to the improvements in DT with regards to its real-time monitoring and forecasting properties. Despite this progress and individual company-based efforts, certain research gaps exist in the field, which have caused delay in the widespread adoption of this concept. We reviewed relevant works and identified that the major reasons for this delay are the lack of a universal reference framework, domain dependence, security concerns of shared data, reliance of digital twin on other technologies, and lack of quantitative metrics. We define the necessary components of a digital twin required for a universal reference framework, which also validate its uniqueness as a concept compared to similar concepts like simulation, autonomous systems, etc. This work further assesses the digital twin applications in different domains and the current state of machine learning and big data in it. It thus answers and identifies novel research questions, both of which will help to better understand and advance the theory and practice of digital twins.
Neural data compression has been shown to outperform classical methods in terms of $RD$ performance, with results still improving rapidly. At a high level, neural compression is based on an autoencoder that tries to reconstruct the input instance from a (quantized) latent representation, coupled with a prior that is used to losslessly compress these latents. Due to limitations on model capacity and imperfect optimization and generalization, such models will suboptimally compress test data in general. However, one of the great strengths of learned compression is that if the test-time data distribution is known and relatively low-entropy (e.g. a camera watching a static scene, a dash cam in an autonomous car, etc.), the model can easily be finetuned or adapted to this distribution, leading to improved $RD$ performance. In this paper we take this concept to the extreme, adapting the full model to a single video, and sending model updates (quantized and compressed using a parameter-space prior) along with the latent representation. Unlike previous work, we finetune not only the encoder/latents but the entire model, and - during finetuning - take into account both the effect of model quantization and the additional costs incurred by sending the model updates. We evaluate an image compression model on I-frames (sampled at 2 fps) from videos of the Xiph dataset, and demonstrate that full-model adaptation improves $RD$ performance by ~1 dB, with respect to encoder-only finetuning.
Accurate and computationally efficient means for classifying human activities have been the subject of extensive research efforts. Most current research focuses on extracting complex features to achieve high classification accuracy. We propose a template selection approach based on Dynamic Time Warping, such that complex feature extraction and domain knowledge is avoided. We demonstrate the predictive capability of the algorithm on both simulated and real smartphone data.
Because the infection by Severe Acute Respiratory Syndrome Coronavirus 2 (COVID-19) causes the pneumonia-like effect in the lungs, the examination of chest x-rays can help to diagnose the diseases. For automatic analysis of images, they are represented in machines by a set of semantic features. Deep Learning (DL) models are widely used to extract features from images. General deep features may not be appropriate to represent chest x-rays as they have a few semantic regions. Though the Bag of Visual Words (BoVW) based features are shown to be more appropriate for x-ray type of images, existing BoVW features may not capture enough information to differentiate COVID-19 infection from other pneumonia-related infections. In this paper, we propose a new BoVW method over deep features, called Bag of Deep Visual Words (BoDVW), by removing the feature map normalization step and adding deep features normalization step on the raw feature maps. This helps to preserve the semantics of each feature map that may have important clues to differentiate COVID-19 from pneumonia. We evaluate the effectiveness of our proposed BoDVW features in chest x-rays classification using Support Vector Machine (SVM) to diagnose COVID-19. Our results on a publicly available COVID-19 x-ray dataset reveal that our features produce stable and prominent classification accuracy, particularly differentiating COVID-19 infection from other pneumonia, in shorter computation time compared to the state-of-the-art methods. Thus, our method could be a very useful tool for quick diagnosis of COVID-19 patients on a large scale.
Despite the recent advances in multiple object tracking (MOT), achieved by joint detection and tracking, dealing with long occlusions remains a challenge. This is due to the fact that such techniques tend to ignore the long-term motion information. In this paper, we introduce a probabilistic autoregressive motion model to score tracklet proposals by directly measuring their likelihood. This is achieved by training our model to learn the underlying distribution of natural tracklets. As such, our model allows us not only to assign new detections to existing tracklets, but also to inpaint a tracklet when an object has been lost for a long time, e.g., due to occlusion, by sampling tracklets so as to fill the gap caused by misdetections. Our experiments demonstrate the superiority of our approach at tracking objects in challenging sequences; it outperforms the state of the art in most standard MOT metrics on multiple MOT benchmark datasets, including MOT16, MOT17, and MOT20.
The digitization of historical maps enables the study of ancient, fragile, unique, and hardly accessible information sources. Main map features can be retrieved and tracked through the time for subsequent thematic analysis. The goal of this work is the vectorization step, i.e., the extraction of vector shapes of the objects of interest from raster images of maps. We are particularly interested in closed shape detection such as buildings, building blocks, gardens, rivers, etc. in order to monitor their temporal evolution. Historical map images present significant pattern recognition challenges. The extraction of closed shapes by using traditional Mathematical Morphology (MM) is highly challenging due to the overlapping of multiple map features and texts. Moreover, state-of-the-art Convolutional Neural Networks (CNN) are perfectly designed for content image filtering but provide no guarantee about closed shape detection. Also, the lack of textural and color information of historical maps makes it hard for CNN to detect shapes that are represented by only their boundaries. Our contribution is a pipeline that combines the strengths of CNN (efficient edge detection and filtering) and MM (guaranteed extraction of closed shapes) in order to achieve such a task. The evaluation of our approach on a public dataset shows its effectiveness for extracting the closed boundaries of objects in historical maps.
Risk-aware control, though with promise to tackle unexpected events, requires a known exact dynamical model. In this work, we propose a model-free framework to learn a risk-aware controller with a focus on the linear system. We formulate it as a discrete-time infinite-horizon LQR problem with a state predictive variance constraint. To solve it, we parameterize the policy with a feedback gain pair and leverage primal-dual methods to optimize it by solely using data. We first study the optimization landscape of the Lagrangian function and establish the strong duality in spite of its non-convex nature. Alongside, we find that the Lagrangian function enjoys an important local gradient dominance property, which is then exploited to develop a convergent random search algorithm to learn the dual function. Furthermore, we propose a primal-dual algorithm with global convergence to learn the optimal policy-multiplier pair. Finally, we validate our results via simulations.
Researchers have used from 30 days to several years of daily returns as source data for clustering financial time series based on their correlations. This paper sets up a statistical framework to study the validity of such practices. We first show that clustering correlated random variables from their observed values is statistically consistent. Then, we also give a first empirical answer to the much debated question: How long should the time series be? If too short, the clusters found can be spurious; if too long, dynamics can be smoothed out.
Trajectory planning is a fundamental task on various autonomous driving platforms, such as social robotics and self-driving cars. Many trajectory planning algorithms use a reference curve based Frenet frame with time to reduce the planning dimension. However, there is a common implicit assumption in classic trajectory planning approaches, which is that the generated trajectory should follow the reference curve continuously. This assumption is not always true in real applications and it might cause some undesired issues in planning. One issue is that the projection of the planned trajectory onto the reference curve maybe discontinuous. Then, some segments on the reference curve are not the image of any part of the planned path. Another issue is that the planned path might self-intersect when following a simple reference curve continuously. The generated trajectories are unnatural and suboptimal ones when these issues happen. In this paper, we firstly demonstrate these issues and then introduce an efficient trajectory generation method which uses a new transformation from the Cartesian frame to Frenet frames. Experimental results on a simulated street scenario demonstrated the effectiveness of the proposed method.