Efficient Analysis of COVID-19 Clinical Data using Machine Learning Models

Because of the rapid spread of COVID-19 to almost every part of the globe, huge volumes of data and case studies have been made available, providing researchers with a unique opportunity to find trends and make discoveries like never before, by leveraging such big data. This data is of many different varieties, and can be of different levels of veracity e.g., precise, imprecise, uncertain, and missing, making it challenging to extract important information from such data. Yet, efficient analyses of this continuously growing and evolving COVID-19 data is crucial to inform -- often in real-time -- the relevant measures needed for controlling, mitigating, and ultimately avoiding viral spread. Applying machine learning based algorithms to this big data is a natural approach to take to this aim, since they can quickly scale to such data, and extract the relevant information in the presence of variety and different levels of veracity. This is important for COVID-19, and for potential future pandemics in general. In this paper, we design a straightforward encoding of clinical data (on categorical attributes) into a fixed-length feature vector representation, and then propose a model that first performs efficient feature selection from such representation. We apply this approach on two clinical datasets of the COVID-19 patients and then apply different machine learning algorithms downstream for classification purposes. We show that with the efficient feature selection algorithm, we can achieve a prediction accuracy of more than 90\% in most cases. We also computed the importance of different attributes in the dataset using information gain. This can help the policy makers to focus on only certain attributes for the purposes of studying this disease rather than focusing on multiple random factors that may not be very informative to patient outcomes.

Mean-based Heuristic Search for Real-Time Planning

In this paper, we introduce a new heuristic search algorithm based on mean values for real-time planning, called MHSP. It consists in associating the principles of UCT, a bandit-based algorithm which gave very good results in computer games, and especially in Computer Go, with heuristic search in order to obtain a real-time planner in the context of classical planning. MHSP is evaluated on different planning problems and compared to existing algorithms performing on-line search and learning. Besides, our results highlight the capacity of MHSP to return plans in a real-time manner which tend to an optimal plan over the time which is faster and of better quality compared to existing algorithms in the literature.

Development of Quantized DNN Library for Exact Hardware Emulation

Quantization is used to speed up execution time and save power when runnning Deep neural networks (DNNs) on edge devices like AI chips. To investigate the effect of quantization, we need performing inference after quantizing the weights of DNN with 32-bit floating-point precision by a some bit width, and then quantizing them back to 32-bit floating-point precision. This is because the DNN library can only handle floating-point numbers. However, the accuracy of the emulation does not provide accurate precision. We need accurate precision to detect overflow in MAC operations or to verify the operation on edge de vices. We have developed PyParch, a DNN library that executes quantized DNNs (QNNs) with exactly the same be havior as hardware. In this paper, we describe a new proposal and implementation of PyParch. As a result of the evaluation, the accuracy of QNNs with arbitrary bit widths can be estimated for la rge and complex DNNs such as YOLOv5, and the overflow can be detected. We evaluated the overhead of the emulation time and found that it was 5.6 times slower for QNN and 42 times slower for QNN with overflow detection compared to the normal DNN execution time.

Fully Spiking Variational Autoencoder

Spiking neural networks (SNNs) can be run on neuromorphic devices with ultra-high speed and ultra-low energy consumption because of their binary and event-driven nature. Therefore, SNNs are expected to have various applications, including as generative models being running on edge devices to create high-quality images. In this study, we build a variational autoencoder (VAE) with SNN to enable image generation. VAE is known for its stability among generative models; recently, its quality advanced. In vanilla VAE, the latent space is represented as a normal distribution, and floating-point calculations are required in sampling. However, this is not possible in SNNs because all features must be binary time series data. Therefore, we constructed the latent space with an autoregressive SNN model, and randomly selected samples from its output to sample the latent variables. This allows the latent variables to follow the Bernoulli process and allows variational learning. Thus, we build the Fully Spiking Variational Autoencoder where all modules are constructed with SNN. To the best of our knowledge, we are the first to build a VAE only with SNN layers. We experimented with several datasets, and confirmed that it can generate images with the same or better quality compared to conventional ANNs. The code will be available soon.

Adaptive Event Detection for Representative Load Signature Extraction

Event detection is the first step in event-based non-intrusive load monitoring (NILM) and it can provide useful transient information to identify appliances. However, existing event detection methods with fixed parameters may fail in case of unpredictable and complicated residential load changes such as high fluctuation, long transition, and near simultaneity. This paper proposes a dynamic time-window approach to deal with these highly complex load variations. Specifically, a window with adaptive margins, multi-timescale window screening, and adaptive threshold (WAMMA) method is proposed to detect events in aggregated home appliance load data with high sampling rate (>1Hz). The proposed method accurately captures the transient process by adaptively tuning parameters including window width, margin width, and change threshold. Furthermore, representative transient and steady-state load signatures are extracted and, for the first time, quantified from transient and steady periods segmented by detected events. Case studies on a 20Hz dataset, the 50Hz LIFTED dataset, and the 60Hz BLUED dataset show that the proposed method can robustly outperform other state-of-art event detection methods. This paper also shows that the extracted load signatures can improve NILM accuracy and help develop other applications such as load reconstruction to generate realistic load data for NILM research.

Evaluation of Thematic Coherence in Microblogs

Collecting together microblogs representing opinions about the same topics within the same timeframe is useful to a number of different tasks and practitioners. A major question is how to evaluate the quality of such thematic clusters. Here we create a corpus of microblog clusters from three different domains and time windows and define the task of evaluating thematic coherence. We provide annotation guidelines and human annotations of thematic coherence by journalist experts. We subsequently investigate the efficacy of different automated evaluation metrics for the task. We consider a range of metrics including surface level metrics, ones for topic model coherence and text generation metrics (TGMs). While surface level metrics perform well, outperforming topic coherence metrics, they are not as consistent as TGMs. TGMs are more reliable than all other metrics considered for capturing thematic coherence in microblog clusters due to being less sensitive to the effect of time windows.

GRU-ODE-Bayes: Continuous modeling of sporadically-observed time series

Modeling real-world multidimensional time series can be particularly challenging when these are sporadically observed (i.e., sampling is irregular both in time and across dimensions)-such as in the case of clinical patient data. To address these challenges, we propose (1) a continuous-time version of the Gated Recurrent Unit, building upon the recent Neural Ordinary Differential Equations (Chen et al., 2018), and (2) a Bayesian update network that processes the sporadic observations. We bring these two ideas together in our GRU-ODE-Bayes method. We then demonstrate that the proposed method encodes a continuity prior for the latent process and that it can exactly represent the Fokker-Planck dynamics of complex processes driven by a multidimensional stochastic differential equation. Additionally, empirical evaluation shows that our method outperforms the state of the art on both synthetic data and real-world data with applications in healthcare and climate forecast. What is more, the continuity prior is shown to be well suited for low number of samples settings.

Automatic Modulation Classification Using Involution Enabled Residual Networks

Automatic modulation classification (AMC) is of crucial importance for realizing wireless intelligence communications. Many deep learning based models especially convolution neural networks (CNNs) have been proposed for AMC. However, the computation cost is very high, which makes them inappropriate for beyond the fifth generation wireless communication networks that have stringent requirements on the classification accuracy and computing time. In order to tackle those challenges, a novel involution enabled AMC scheme is proposed by using the bottleneck structure of the residual networks. Involution is utilized instead of convolution to enhance the discrimination capability and expressiveness of the model by incorporating a self-attention mechanism. Simulation results demonstrate that our proposed scheme achieves superior classification performance and faster convergence speed comparing with other benchmark schemes.

Automated triaging of head MRI examinations using convolutional neural networks

The growing demand for head magnetic resonance imaging (MRI) examinations, along with a global shortage of radiologists, has led to an increase in the time taken to report head MRI scans around the world. For many neurological conditions, this delay can result in increased morbidity and mortality. An automated triaging tool could reduce reporting times for abnormal examinations by identifying abnormalities at the time of imaging and prioritizing the reporting of these scans. In this work, we present a convolutional neural network for detecting clinically-relevant abnormalities in $\text{T}_2$-weighted head MRI scans. Using a validated neuroradiology report classifier, we generated a labelled dataset of 43,754 scans from two large UK hospitals for model training, and demonstrate accurate classification (area under the receiver operating curve (AUC) = 0.943) on a test set of 800 scans labelled by a team of neuroradiologists. Importantly, when trained on scans from only a single hospital the model generalized to scans from the other hospital ($\Delta$AUC $\leq$ 0.02). A simulation study demonstrated that our model would reduce the mean reporting time for abnormal examinations from 28 days to 14 days and from 9 days to 5 days at the two hospitals, demonstrating feasibility for use in a clinical triage environment.

Lightweight Network Architecture for Real-Time Action Recognition

In this work we present a new efficient approach to Human Action Recognition called Video Transformer Network (VTN). It leverages the latest advances in Computer Vision and Natural Language Processing and applies them to video understanding. The proposed method allows us to create lightweight CNN models that achieve high accuracy and real-time speed using just an RGB mono camera and general purpose CPU. Furthermore, we explain how to improve accuracy by distilling from multiple models with different modalities into a single model. We conduct a comparison with state-of-the-art methods and show that our approach performs on par with most of them on famous Action Recognition datasets. We benchmark the inference time of the models using the modern inference framework and argue that our approach compares favorably with other methods in terms of speed/accuracy trade-off, running at 56 FPS on CPU. The models and the training code are available.