There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using 277 billion words of mixed clinical and English text with a GPT-3 architecture of 20 billion parameters. GatorTronGPT improves biomedical natural language processing for medical research. Synthetic NLP models trained using GatorTronGPT generated text outperform NLP models trained using real-world clinical text. Physicians Turing test using 1 (worst) to 9 (best) scale shows that there is no significant difference in linguistic readability (p = 0.22; 6.57 of GatorTronGPT compared with 6.93 of human) and clinical relevance (p = 0.91; 7.0 of GatorTronGPT compared with 6.97 of human) and that physicians cannot differentiate them (p < 0.001). This study provides insights on the opportunities and challenges of LLMs for medical research and healthcare.
Named entity recognition in real-world applications suffers from the diversity of entity types, the emergence of new entity types, and the lack of high-quality annotations. To address the above problems, this paper proposes an in-context learning-based NER approach, which can effectively inject in-context NER ability into PLMs and recognize entities of novel types on-the-fly using only a few demonstrative instances. Specifically, we model PLMs as a meta-function $\mathcal{ \lambda_ {\text{instruction, demonstrations, text}}. M}$, and a new entity extractor can be implicitly constructed by applying new instruction and demonstrations to PLMs, i.e., $\mathcal{ (\lambda . M) }$(instruction, demonstrations) $\to$ $\mathcal{F}$ where $\mathcal{F}$ will be a new entity extractor, i.e., $\mathcal{F}$: text $\to$ entities. To inject the above in-context NER ability into PLMs, we propose a meta-function pre-training algorithm, which pre-trains PLMs by comparing the (instruction, demonstration)-initialized extractor with a surrogate golden extractor. Experimental results on 4 few-shot NER datasets show that our method can effectively inject in-context NER ability into PLMs and significantly outperforms the PLMs+fine-tuning counterparts.
Optimizing the phrasing of argumentative text is crucial in higher education and professional development. However, assessing whether and how the different claims in a text should be revised is a hard task, especially for novice writers. In this work, we explore the main challenges to identifying argumentative claims in need of specific revisions. By learning from collaborative editing behaviors in online debates, we seek to capture implicit revision patterns in order to develop approaches aimed at guiding writers in how to further improve their arguments. We systematically compare the ability of common word embedding models to capture the differences between different versions of the same text, and we analyze their impact on various types of writing issues. To deal with the noisy nature of revision-based corpora, we propose a new sampling strategy based on revision distance. Opposed to approaches from prior work, such sampling can be done without employing additional annotations and judgments. Moreover, we provide evidence that using contextual information and domain knowledge can further improve prediction results. How useful a certain type of context is, depends on the issue the claim is suffering from, though.
Diffusion models have demonstrated excellent potential for generating diverse images. However, their performance often suffers from slow generation due to iterative denoising. Knowledge distillation has been recently proposed as a remedy that can reduce the number of inference steps to one or a few without significant quality degradation. However, existing distillation methods either require significant amounts of offline computation for generating synthetic training data from the teacher model or need to perform expensive online learning with the help of real data. In this work, we present a novel technique called BOOT, that overcomes these limitations with an efficient data-free distillation algorithm. The core idea is to learn a time-conditioned model that predicts the output of a pre-trained diffusion model teacher given any time step. Such a model can be efficiently trained based on bootstrapping from two consecutive sampled steps. Furthermore, our method can be easily adapted to large-scale text-to-image diffusion models, which are challenging for conventional methods given the fact that the training sets are often large and difficult to access. We demonstrate the effectiveness of our approach on several benchmark datasets in the DDIM setting, achieving comparable generation quality while being orders of magnitude faster than the diffusion teacher. The text-to-image results show that the proposed approach is able to handle highly complex distributions, shedding light on more efficient generative modeling.
Interstitial lung diseases (ILD) present diagnostic challenges due to their varied manifestations and overlapping imaging features. To address this, we propose a machine learning approach that utilizes CLIP, a multimodal (image and text) self-supervised model, for ILD classification. We extensively integrate zero-shot CLIP throughout our workflow, starting from the initial extraction of image patches from volumetric CT scans and proceeding to ILD classification using "patch montages". Furthermore, we investigate how domain adaptive pretraining (DAPT) CLIP with task-specific images (CT "patch montages" extracted with ILD-specific prompts for CLIP) and/or text (lung-specific sections of radiology reports) affects downstream ILD classification performance. By leveraging CLIP-extracted "patch montages" and DAPT, we achieve strong zero-shot ILD classification results, including an AUROC of 0.893, without the need for any labeled training data. This work highlights the versatility and potential of multimodal models like CLIP for medical image classification tasks where labeled data is scarce.
We propose a method to control the attributes of Language Models (LMs) for the text generation task using Causal Average Treatment Effect (ATE) scores and counterfactual augmentation. We explore this method, in the context of LM detoxification, and propose the Causally Fair Language (CFL) architecture for detoxifying pre-trained LMs in a plug-and-play manner. Our architecture is based on a Structural Causal Model (SCM) that is mathematically transparent and computationally efficient as compared with many existing detoxification techniques. We also propose several new metrics that aim to better understand the behaviour of LMs in the context of toxic text generation. Further, we achieve state of the art performance for toxic degeneration, which are computed using \RTP (RTP) benchmark. Our experiments show that CFL achieves such a detoxification without much impact on the model perplexity. We also show that CFL mitigates the unintended bias problem through experiments on the BOLD dataset.
Natural Language Processing (NLP) domain is experiencing a revolution due to the capabilities of Pre-trained Large Language Models ( LLMs), fueled by ground-breaking Transformers architecture, resulting into unprecedented advancements. Their exceptional aptitude for assessing probability distributions of text sequences is the primary catalyst for outstanding improvement of both the precision and efficiency of NLP models. This paper introduces for the first time SecurityLLM, a pre-trained language model designed for cybersecurity threats detection. The SecurityLLM model is articulated around two key generative elements: SecurityBERT and FalconLLM. SecurityBERT operates as a cyber threat detection mechanism, while FalconLLM is an incident response and recovery system. To the best of our knowledge, SecurityBERT represents the inaugural application of BERT in cyber threat detection. Despite the unique nature of the input data and features, such as the reduced significance of syntactic structures in content classification, the suitability of BERT for this duty demonstrates unexpected potential, thanks to our pioneering study. We reveal that a simple classification model, created from scratch, and consolidated with LLMs, exceeds the performance of established traditional Machine Learning (ML) and Deep Learning (DL) methods in cyber threat detection, like Convolutional Neural Networks (CNN) or Recurrent Neural Networks (RNN). The experimental analysis, conducted using a collected cybersecurity dataset, proves that our SecurityLLM model can identify fourteen (14) different types of attacks with an overall accuracy of 98%
Labels noise refers to errors in training labels caused by cheap data annotation methods, such as web scraping or crowd-sourcing, which can be detrimental to the performance of supervised classifiers. Several methods have been proposed to counteract the effect of random label noise in supervised classification, and some studies have shown that BERT is already robust against high rates of randomly injected label noise. However, real label noise is not random; rather, it is often correlated with input features or other annotator-specific factors. In this paper, we evaluate BERT in the presence of two types of realistic label noise: feature-dependent label noise, and synthetic label noise from annotator disagreements. We show that the presence of these types of noise significantly degrades BERT classification performance. To improve robustness, we evaluate different types of ensembles and noise-cleaning methods and compare their effectiveness against label noise across different datasets.
While summarization has been extensively researched in natural language processing (NLP), cross-lingual cross-temporal summarization (CLCTS) is a largely unexplored area that has the potential to improve cross-cultural accessibility, information sharing, and understanding. This paper comprehensively addresses the CLCTS task, including dataset creation, modeling, and evaluation. We build the first CLCTS corpus, leveraging historical fictive texts and Wikipedia summaries in English and German, and examine the effectiveness of popular transformer end-to-end models with different intermediate task finetuning tasks. Additionally, we explore the potential of ChatGPT for CLCTS as a summarizer and an evaluator. Overall, we report evaluations from humans, ChatGPT, and several recent automatic evaluation metrics where we find our intermediate task finetuned end-to-end models generate bad to moderate quality summaries; ChatGPT as a summarizer (without any finetuning) provides moderate to good quality outputs and as an evaluator correlates moderately with human evaluations though it is prone to giving lower scores. ChatGPT also seems to be very adept at normalizing historical text. We finally test ChatGPT in a scenario with adversarially attacked and unseen source documents and find that ChatGPT is better at omission and entity swap than negating against its prior knowledge.
Visual foundation models like CLIP excel in learning feature representations from extensive datasets through self-supervised methods, demonstrating remarkable transfer learning and generalization capabilities. A growing number of applications based on visual foundation models are emerging, including innovative solutions such as BLIP-2. These applications employ pre-trained CLIP models as upstream feature extractors and train various downstream modules to accomplish diverse tasks. In situations involving system upgrades that require updating the upstream foundation model, it becomes essential to re-train all downstream modules to adapt to the new foundation model, which is inflexible and inefficient. In this paper, we introduce a parameter-efficient and task-agnostic adapter, dubbed TaCA, that facilitates compatibility across distinct foundation models while ensuring enhanced performance for the new models. TaCA allows downstream applications to seamlessly integrate better-performing foundation models without necessitating retraining. We conduct extensive experimental validation of TaCA using different scales of models with up to one billion parameters on various tasks such as video-text retrieval, video recognition, and visual question answering. The results consistently demonstrate the emergent ability of TaCA on hot-plugging upgrades for visual foundation models. Codes and models will be available at https://github.com/TencentARC/TaCA.