Access to medical data is often limited as it contains protected health information (PHI). There are privacy concerns regarding using records containing personally identifiable information. Recent advancements have been made in applying deep learning-based algorithms for clinical diagnosis and decision-making. However, deep learning models are data-greedy, whereas the availability of medical datasets for training and evaluating these models is relatively limited. Data augmentation with so-called \textit{digital twins} is an emerging technique to address this need. This paper presents a novel approach for generating synthetic electrocardiogram (ECG) images with realistic artifacts from time-series data for use in developing algorithms for digitization of ECG images. Synthetic data is generated in a privacy-preserving manner by generating distortionless ECG images on standard ECG paper background. Next, various distortions, including handwritten text artifacts, wrinkles, creases, and perspective transforms are applied to the ECG images. The artifacts are generated synthetically, without personally identifiable information. As a use case, we generated a large ECG image dataset of 21,801 records from the PhysioNet PTB-XL dataset, with 12 lead ECG time-series data from 18,869 patients. A deep ECG image digitization model was developed and trained on the synthetic dataset, and was employed to convert the synthetic images to time-series data for evaluation. The signal-to-noise ratio (SNR) was calculated to assess the image digitization quality vs the ground truth ECG time-series. The results show an average signal recovery SNR of 27$\pm$2.8\,dB, demonstrating the significance of the proposed synthetic ECG image dataset for training deep learning models.
We aimed to investigate the impact of social circumstances on cancer therapy selection using natural language processing to derive insights from social worker documentation. We developed and employed a Bidirectional Encoder Representations from Transformers (BERT) based approach, using a hierarchical multi-step BERT model (BERT-MS) to predict the prescription of targeted cancer therapy to patients based solely on documentation by clinical social workers. Our corpus included free-text clinical social work notes, combined with medication prescription information, for all patients treated for breast cancer. We conducted a feature importance analysis to pinpoint the specific social circumstances that impact cancer therapy selection. Using only social work notes, we consistently predicted the administration of targeted therapies, suggesting systematic differences in treatment selection exist due to non-clinical factors. The UCSF-BERT model, pretrained on clinical text at UCSF, outperformed other publicly available language models with an AUROC of 0.675 and a Macro F1 score of 0.599. The UCSF BERT-MS model, capable of leveraging multiple pieces of notes, surpassed the UCSF-BERT model in both AUROC and Macro-F1. Our feature importance analysis identified several clinically intuitive social determinants of health (SDOH) that potentially contribute to disparities in treatment. Our findings indicate that significant disparities exist among breast cancer patients receiving different types of therapies based on social determinants of health. Social work reports play a crucial role in understanding these disparities in clinical decision-making.
End-to-end speech translation (ST) is the task of translating speech signals in the source language into text in the target language. As a cross-modal task, end-to-end ST is difficult to train with limited data. Existing methods often try to transfer knowledge from machine translation (MT), but their performances are restricted by the modality gap between speech and text. In this paper, we propose Cross-modal Mixup via Optimal Transport CMOT to overcome the modality gap. We find the alignment between speech and text sequences via optimal transport and then mix up the sequences from different modalities at a token level using the alignment. Experiments on the MuST-C ST benchmark demonstrate that CMOT achieves an average BLEU of 30.0 in 8 translation directions, outperforming previous methods. Further analysis shows CMOT can adaptively find the alignment between modalities, which helps alleviate the modality gap between speech and text. Code is publicly available at https://github.com/ictnlp/CMOT.
Automated audio captioning is multi-modal translation task that aim to generate textual descriptions for a given audio clip. In this paper we propose a full Transformer architecture that utilizes Patchout as proposed in [1], significantly reducing the computational complexity and avoiding overfitting. The caption generation is partly conditioned on textual AudioSet tags extracted by a pre-trained classification model which is fine-tuned to maximize the semantic similarity between AudioSet labels and ground truth captions. To mitigate the data scarcity problem of Automated Audio Captioning we introduce transfer learning from an upstream audio-related task and an enlarged in-domain dataset. Moreover, we propose a method to apply Mixup augmentation for AAC. Ablation studies are carried out to investigate how Patchout and text guidance contribute to the final performance. The results show that the proposed techniques improve the performance of our system and while reducing the computational complexity. Our proposed method received the Judges Award at the Task6A of DCASE Challenge 2022.
Generative AI has made significant strides in computer vision, particularly in image/video synthesis conditioned on text descriptions. Despite the advancements, it remains challenging especially in the generation of human-centric content such as dance synthesis. Existing dance synthesis methods struggle with the gap between synthesized content and real-world dance scenarios. In this paper, we define a new problem setting: Referring Human Dance Generation, which focuses on real-world dance scenarios with three important properties: (i) Faithfulness: the synthesis should retain the appearance of both human subject foreground and background from the reference image, and precisely follow the target pose; (ii) Generalizability: the model should generalize to unseen human subjects, backgrounds, and poses; (iii) Compositionality: it should allow for composition of seen/unseen subjects, backgrounds, and poses from different sources. To address these challenges, we introduce a novel approach, DISCO, which includes a novel model architecture with disentangled control to improve the faithfulness and compositionality of dance synthesis, and an effective human attribute pre-training for better generalizability to unseen humans. Extensive qualitative and quantitative results demonstrate that DISCO can generate high-quality human dance images and videos with diverse appearances and flexible motions. Code, demo, video and visualization are available at: https://disco-dance.github.io/.
Autoregressive large language models (LLMs) have made remarkable progress in various natural language generation tasks. However, they incur high computation cost and latency resulting from the autoregressive token-by-token generation. To address this issue, several approaches have been proposed to reduce computational cost using early-exit strategies. These strategies enable faster text generation using reduced computation without applying the full computation graph to each token. While existing token-level early exit methods show promising results for online inference, they cannot be readily applied for batch inferencing and Key-Value caching. This is because they have to wait until the last token in a batch exits before they can stop computing. This severely limits the practical application of such techniques. In this paper, we propose a simple and effective token-level early exit method, SkipDecode, designed to work seamlessly with batch inferencing and KV caching. It overcomes prior constraints by setting up a singular exit point for every token in a batch at each sequence position. It also guarantees a monotonic decrease in exit points, thereby eliminating the need to recompute KV Caches for preceding tokens. Rather than terminating computation prematurely as in prior works, our approach bypasses lower to middle layers, devoting most of the computational resources to upper layers, allowing later tokens to benefit from the compute expenditure by earlier tokens. Our experimental results show that SkipDecode can obtain 2x to 5x inference speedups with negligible regression across a variety of tasks. This is achieved using OPT models of 1.3 billion and 6.7 billion parameters, all the while being directly compatible with batching and KV caching optimization techniques.
Diffusion models have shown significant progress in image translation tasks recently. However, due to their stochastic nature, there's often a trade-off between style transformation and content preservation. Current strategies aim to disentangle style and content, preserving the source image's structure while successfully transitioning from a source to a target domain under text or one-shot image conditions. Yet, these methods often require computationally intense fine-tuning of diffusion models or additional neural networks. To address these challenges, here we present an approach that guides the reverse process of diffusion sampling by applying asymmetric gradient guidance. This results in quicker and more stable image manipulation for both text-guided and image-guided image translation. Our model's adaptability allows it to be implemented with both image- and latent-diffusion models. Experiments show that our method outperforms various state-of-the-art models in image translation tasks.
One of the major problems with text simplification is the lack of high-quality data. The sources of simplification datasets are limited to Wikipedia and Newsela, restricting further development of this field. In this paper, we analyzed the similarity between text summarization and text simplification and exploited summarization data to help simplify. First, we proposed an alignment algorithm to extract sentence pairs from summarization datasets. Then, we designed four attributes to characterize the degree of simplification and proposed a method to filter suitable pairs. We named these pairs Sum4Simp (S4S). Next, we conducted human evaluations to show that S4S is high-quality and compared it with a real simplification dataset. Finally, we conducted experiments to illustrate that the S4S can improve the performance of several mainstream simplification models, especially in low-resource scenarios.
We present MAV3D (Make-A-Video3D), a method for generating three-dimensional dynamic scenes from text descriptions. Our approach uses a 4D dynamic Neural Radiance Field (NeRF), which is optimized for scene appearance, density, and motion consistency by querying a Text-to-Video (T2V) diffusion-based model. The dynamic video output generated from the provided text can be viewed from any camera location and angle, and can be composited into any 3D environment. MAV3D does not require any 3D or 4D data and the T2V model is trained only on Text-Image pairs and unlabeled videos. We demonstrate the effectiveness of our approach using comprehensive quantitative and qualitative experiments and show an improvement over previously established internal baselines. To the best of our knowledge, our method is the first to generate 3D dynamic scenes given a text description.
In the multimedia era, image is an effective medium in search advertising. Dynamic Image Advertising (DIA), a system that matches queries with ad images and generates multimodal ads, is introduced to improve user experience and ad revenue. The core of DIA is a query-image matching module performing ad image retrieval and relevance modeling. Current query-image matching suffers from limited and inconsistent data, and insufficient cross-modal interaction. Also, the separate optimization of retrieval and relevance models affects overall performance. To address this issue, we propose a vision-language framework consisting of two parts. First, we train a base model on large-scale image-text pairs to learn general multimodal representation. Then, we fine-tune the base model on advertising business data, unifying relevance modeling and retrieval through multi-objective learning. Our framework has been implemented in Baidu search advertising system "Phoneix Nest". Online evaluation shows that it improves cost per mille (CPM) and click-through rate (CTR) by 1.04% and 1.865%.