Towards Explainable Automated Neuroanatomy

We present a novel method for quantifying the microscopic structure of brain tissue. It is based on the automated recognition of interpretable features obtained by analyzing the shapes of cells. This contrasts with prevailing methods of brain anatomical analysis in two ways. First, contemporary methods use gray-scale values derived from smoothed version of the anatomical images, which dissipated valuable information from the texture of the images. Second, contemporary analysis uses the output of black-box Convolutional Neural Networks, while our system makes decisions based on interpretable features obtained by analyzing the shapes of individual cells. An important benefit of this open-box approach is that the anatomist can understand and correct the decisions made by the computer. Our proposed system can accurately localize and identify existing brain structures. This can be used to align and coregistar brains and will facilitate connectomic studies for reverse engineering of brain circuitry.

Anatomical Conditioning for Contrastive Unpaired Image-to-Image Translation of Optical Coherence Tomography Images

For a unified analysis of medical images from different modalities, data harmonization using image-to-image (I2I) translation is desired. We study this problem employing an optical coherence tomography (OCT) data set of Spectralis-OCT and Home-OCT images. I2I translation is challenging because the images are unpaired, and a bijective mapping does not exist due to the information discrepancy between both domains. This problem has been addressed by the Contrastive Learning for Unpaired I2I Translation (CUT) approach, but it reduces semantic consistency. To restore the semantic consistency, we support the style decoder using an additional segmentation decoder. Our approach increases the similarity between the style-translated images and the target distribution. Importantly, we improve the segmentation of biomarkers in Home-OCT images in an unsupervised domain adaptation scenario. Our data harmonization approach provides potential for the monitoring of diseases, e.g., age related macular disease, using different OCT devices.

Online Self-body Image Acquisition Considering Changes in Muscle Routes Caused by Softness of Body Tissue for Tendon-driven Musculoskeletal Humanoids

Tendon-driven musculoskeletal humanoids have many benefits in terms of the flexible spine, multiple degrees of freedom, and variable stiffness. At the same time, because of its body complexity, there are problems in controllability. First, due to the large difference between the actual robot and its geometric model, it cannot move as intended and large internal muscle tension may emerge. Second, movements which do not appear as changes in muscle lengths may emerge, because of the muscle route changes caused by softness of body tissue. To solve these problems, we construct two models: ideal joint-muscle model and muscle-route change model, using a neural network. We initialize these models by a man-made geometric model and update them online using the sensor information of the actual robot. We validate that the tendon-driven musculoskeletal humanoid Kengoro is able to obtain a correct self-body image through several experiments.

Wi-Fi-based Personnel Identity Recognition: Addressing Dataset Imbalance with C-DDPMs

Wireless sensing technologies become increasingly prevalent due to the ubiquitous nature of wireless signals and their inherent privacy-friendly characteristics. Device-free personnel identity recognition, a prevalent application in wireless sensing, is susceptibly challenged by imbalanced channel state information (CSI) datasets. This letter proposes a novel method for CSI dataset augmentation that employs Conditional Denoising Diffusion Probabilistic Models (C-DDPMs) to generate additional samples that address class imbalance issues. The augmentation markedly improves classification accuracies on our homemade dataset, elevating all classes to above 94%.

Comparing Two Model Designs for Clinical Note Generation; Is an LLM a Useful Evaluator of Consistency?

Following an interaction with a patient, physicians are responsible for the submission of clinical documentation, often organized as a SOAP note. A clinical note is not simply a summary of the conversation but requires the use of appropriate medical terminology. The relevant information can then be extracted and organized according to the structure of the SOAP note. In this paper we analyze two different approaches to generate the different sections of a SOAP note based on the audio recording of the conversation, and specifically examine them in terms of note consistency. The first approach generates the sections independently, while the second method generates them all together. In this work we make use of PEGASUS-X Transformer models and observe that both methods lead to similar ROUGE values (less than 1% difference) and have no difference in terms of the Factuality metric. We perform a human evaluation to measure aspects of consistency and demonstrate that LLMs like Llama2 can be used to perform the same tasks with roughly the same agreement as the human annotators. Between the Llama2 analysis and the human reviewers we observe a Cohen Kappa inter-rater reliability of 0.79, 1.00, and 0.32 for consistency of age, gender, and body part injury, respectively. With this we demonstrate the usefulness of leveraging an LLM to measure quality indicators that can be identified by humans but are not currently captured by automatic metrics. This allows scaling evaluation to larger data sets, and we find that clinical note consistency improves by generating each new section conditioned on the output of all previously generated sections.

LATUP-Net: A Lightweight 3D Attention U-Net with Parallel Convolutions for Brain Tumor Segmentation

Early-stage 3D brain tumor segmentation from magnetic resonance imaging (MRI) scans is crucial for prompt and effective treatment. However, this process faces the challenge of precise delineation due to the tumors' complex heterogeneity. Moreover, energy sustainability targets and resource limitations, especially in developing countries, require efficient and accessible medical imaging solutions. The proposed architecture, a Lightweight 3D ATtention U-Net with Parallel convolutions, LATUP-Net, addresses these issues. It is specifically designed to reduce computational requirements significantly while maintaining high segmentation performance. By incorporating parallel convolutions, it enhances feature representation by capturing multi-scale information. It further integrates an attention mechanism to refine segmentation through selective feature recalibration. LATUP-Net achieves promising segmentation performance: the average Dice scores for the whole tumor, tumor core, and enhancing tumor on the BraTS2020 dataset are 88.41%, 83.82%, and 73.67%, and on the BraTS2021 dataset, they are 90.29%, 89.54%, and 83.92%, respectively. Hausdorff distance metrics further indicate its improved ability to delineate tumor boundaries. With its significantly reduced computational demand using only 3.07 M parameters, about 59 times fewer than other state-of-the-art models, and running on a single V100 GPU, LATUP-Net stands out as a promising solution for real-world clinical applications, particularly in settings with limited resources. Investigations into the model's interpretability, utilizing gradient-weighted class activation mapping and confusion matrices, reveal that while attention mechanisms enhance the segmentation of small regions, their impact is nuanced. Achieving the most accurate tumor delineation requires carefully balancing local and global features.

Khayyam Challenge (PersianMMLU): Is Your LLM Truly Wise to The Persian Language?

Evaluating Large Language Models (LLMs) is challenging due to their generative nature, necessitating precise evaluation methodologies. Additionally, non-English LLM evaluation lags behind English, resulting in the absence or weakness of LLMs for many languages. In response to this necessity, we introduce Khayyam Challenge (also known as PersianMMLU), a meticulously curated collection comprising 20,192 four-choice questions sourced from 38 diverse tasks extracted from Persian examinations, spanning a wide spectrum of subjects, complexities, and ages. The primary objective of the Khayyam Challenge is to facilitate the rigorous evaluation of LLMs that support the Persian language. Distinctive features of the Khayyam Challenge are (i) its comprehensive coverage of various topics, including literary comprehension, mathematics, sciences, logic, intelligence testing, etc., aimed at assessing different facets of LLMs such as language comprehension, reasoning, and information retrieval across various educational stages, from lower primary school to upper secondary school (ii) its inclusion of rich metadata such as human response rates, difficulty levels, and descriptive answers (iii) its utilization of new data to avoid data contamination issues prevalent in existing frameworks (iv) its use of original, non-translated data tailored for Persian speakers, ensuring the framework is free from translation challenges and errors while encompassing cultural nuances (v) its inherent scalability for future data updates and evaluations without requiring special human effort. Previous works lacked an evaluation framework that combined all of these features into a single comprehensive benchmark. Furthermore, we evaluate a wide range of existing LLMs that support the Persian language, with statistical analyses and interpretations of their outputs.

Aggressive or Imperceptible, or Both: Network Pruning Assisted Hybrid Byzantines in Federated Learning

Federated learning (FL) has been introduced to enable a large number of clients, possibly mobile devices, to collaborate on generating a generalized machine learning model thanks to utilizing a larger number of local samples without sharing to offer certain privacy to collaborating clients. However, due to the participation of a large number of clients, it is often difficult to profile and verify each client, which leads to a security threat that malicious participants may hamper the accuracy of the trained model by conveying poisoned models during the training. Hence, the aggregation framework at the parameter server also needs to minimize the detrimental effects of these malicious clients. A plethora of attack and defence strategies have been analyzed in the literature. However, often the Byzantine problem is analyzed solely from the outlier detection perspective, being oblivious to the topology of neural networks (NNs). In the scope of this work, we argue that by extracting certain side information specific to the NN topology, one can design stronger attacks. Hence, inspired by the sparse neural networks, we introduce a hybrid sparse Byzantine attack that is composed of two parts: one exhibiting a sparse nature and attacking only certain NN locations with higher sensitivity, and the other being more silent but accumulating over time, where each ideally targets a different type of defence mechanism, and together they form a strong but imperceptible attack. Finally, we show through extensive simulations that the proposed hybrid Byzantine attack is effective against 8 different defence methods.

Privacy-Preserving Deep Learning Using Deformable Operators for Secure Task Learning

In the era of cloud computing and data-driven applications, it is crucial to protect sensitive information to maintain data privacy, ensuring truly reliable systems. As a result, preserving privacy in deep learning systems has become a critical concern. Existing methods for privacy preservation rely on image encryption or perceptual transformation approaches. However, they often suffer from reduced task performance and high computational costs. To address these challenges, we propose a novel Privacy-Preserving framework that uses a set of deformable operators for secure task learning. Our method involves shuffling pixels during the analog-to-digital conversion process to generate visually protected data. Those are then fed into a well-known network enhanced with deformable operators. Using our approach, users can achieve equivalent performance to original images without additional training using a secret key. Moreover, our method enables access control against unauthorized users. Experimental results demonstrate the efficacy of our approach, showcasing its potential in cloud-based scenarios and privacy-sensitive applications.

Sensing-Resistance-Oriented Beamforming for Privacy Protection from ISAC Devices

With the evolution of integrated sensing and communication (ISAC) technology, a growing number of devices go beyond conventional communication functions with sensing abilities. Therefore, future networks are divinable to encounter new privacy concerns on sensing, such as the exposure of position information to unintended receivers. In contrast to traditional privacy preserving schemes aiming to prevent eavesdropping, this contribution conceives a novel beamforming design toward sensing resistance (SR). Specifically, we expect to guarantee the communication quality while masking the real direction of the SR transmitter during the communication. To evaluate the SR performance, a metric termed angular-domain peak-to-average ratio (ADPAR) is first defined and analyzed. Then, we resort to the null-space technique to conceal the real direction, hence to convert the optimization problem to a more tractable form. Moreover, semidefinite relaxation along with index optimization is further utilized to obtain the optimal beamformer. Finally, simulation results demonstrate the feasibility of the proposed SR-oriented beamforming design toward privacy protection from ISAC receivers.