Volumetric optical microscopy using non-diffracting beams enables rapid imaging of 3D volumes by projecting them axially to 2D images but lacks crucial depth information. Addressing this, we introduce MicroDiffusion, a pioneering tool facilitating high-quality, depth-resolved 3D volume reconstruction from limited 2D projections. While existing Implicit Neural Representation (INR) models often yield incomplete outputs and Denoising Diffusion Probabilistic Models (DDPM) excel at capturing details, our method integrates INR's structural coherence with DDPM's fine-detail enhancement capabilities. We pretrain an INR model to transform 2D axially-projected images into a preliminary 3D volume. This pretrained INR acts as a global prior guiding DDPM's generative process through a linear interpolation between INR outputs and noise inputs. This strategy enriches the diffusion process with structured 3D information, enhancing detail and reducing noise in localized 2D images. By conditioning the diffusion model on the closest 2D projection, MicroDiffusion substantially enhances fidelity in resulting 3D reconstructions, surpassing INR and standard DDPM outputs with unparalleled image quality and structural fidelity. Our code and dataset are available at https://github.com/UCSC-VLAA/MicroDiffusion.
Infrared small object detection is an important computer vision task involving the recognition and localization of tiny objects in infrared images, which usually contain only a few pixels. However, it encounters difficulties due to the diminutive size of the objects and the generally complex backgrounds in infrared images. In this paper, we propose a deep learning method, HCF-Net, that significantly improves infrared small object detection performance through multiple practical modules. Specifically, it includes the parallelized patch-aware attention (PPA) module, dimension-aware selective integration (DASI) module, and multi-dilated channel refiner (MDCR) module. The PPA module uses a multi-branch feature extraction strategy to capture feature information at different scales and levels. The DASI module enables adaptive channel selection and fusion. The MDCR module captures spatial features of different receptive field ranges through multiple depth-separable convolutional layers. Extensive experimental results on the SIRST infrared single-frame image dataset show that the proposed HCF-Net performs well, surpassing other traditional and deep learning models. Code is available at https://github.com/zhengshuchen/HCFNet.
Existing medical image registration algorithms rely on either dataset specific training or local texture-based features to align images. The former cannot be reliably implemented without large modality-specific training datasets, while the latter lacks global semantics thus could be easily trapped at local minima. In this paper, we present a training-free deformable image registration method, DINO-Reg, leveraging a general purpose image encoder DINOv2 for image feature extraction. The DINOv2 encoder was trained using the ImageNet data containing natural images. We used the pretrained DINOv2 without any finetuning. Our method feeds the DINOv2 encoded features into a discrete optimizer to find the optimal deformable registration field. We conducted a series of experiments to understand the behavior and role of such a general purpose image encoder in the application of image registration. Combined with handcrafted features, our method won the first place in the recent OncoReg Challenge. To our knowledge, this is the first application of general vision foundation models in medical image registration.
Medical data often exhibits distribution shifts, which cause test-time performance degradation for deep learning models trained using standard supervised learning pipelines. This challenge is addressed in the field of Domain Generalization (DG) with the sub-field of Single Domain Generalization (SDG) being specifically interesting due to the privacy- or logistics-related issues often associated with medical data. Existing disentanglement-based SDG methods heavily rely on structural information embedded in segmentation masks, however classification labels do not provide such dense information. This work introduces a novel SDG method aimed at medical image classification that leverages channel-wise contrastive disentanglement. It is further enhanced with reconstruction-based style regularization to ensure extraction of distinct style and structure feature representations. We evaluate our method on the complex task of multicenter histopathology image classification, comparing it against state-of-the-art (SOTA) SDG baselines. Results demonstrate that our method surpasses the SOTA by a margin of 1% in average accuracy while also showing more stable performance. This study highlights the importance and challenges of exploring SDG frameworks in the context of the classification task. The code is publicly available at https://github.com/BioMedIA-MBZUAI/ConDiSR
The CLIP (Contrastive Language-Image Pretraining) model has exhibited outstanding performance in recognition problems, such as zero-shot image classification and object detection. However, its ability to count remains understudied due to the inherent challenges of transforming counting--a regression task--into a recognition task. In this paper, we investigate CLIP's potential in counting, focusing specifically on estimating crowd sizes. Existing classification-based crowd-counting methods have encountered issues, including inappropriate discretization strategies, which impede the application of CLIP and result in suboptimal performance. To address these challenges, we propose the Enhanced Blockwise Classification (EBC) framework. In contrast to previous methods, EBC relies on integer-valued bins that facilitate the learning of robust decision boundaries. Within our model-agnostic EBC framework, we introduce CLIP-EBC, the first fully CLIP-based crowd-counting model capable of generating density maps. Comprehensive evaluations across diverse crowd-counting datasets demonstrate the state-of-the-art performance of our methods. Particularly, EBC can improve existing models by up to 76.9%. Moreover, our CLIP-EBC model surpasses current crowd-counting methods, achieving mean absolute errors of 55.0 and 6.3 on ShanghaiTech part A and part B datasets, respectively. The code will be made publicly available.
Large-scale generative models have demonstrated impressive capacity in producing visually compelling images, with increasing applications in medical imaging. However, they continue to grapple with the challenge of image hallucination and the generation of anatomically inaccurate outputs. These limitations are mainly due to the sole reliance on textual inputs and lack of spatial control over the generated images, hindering the potential usefulness of such models in real-life settings. We present XReal, a novel controllable diffusion model for generating realistic chest X-ray images through precise anatomy and pathology location control. Our lightweight method can seamlessly integrate spatial control in a pre-trained text-to-image diffusion model without fine-tuning, retaining its existing knowledge while enhancing its generation capabilities. XReal outperforms state-of-the-art x-ray diffusion models in quantitative and qualitative metrics while showing 13% and 10% anatomy and pathology realism gain, respectively, based on the expert radiologist evaluation. Our model holds promise for advancing generative models in medical imaging, offering greater precision and adaptability while inviting further exploration in this evolving field. A large synthetically generated data with annotations and code is publicly available at https://github.com/BioMedIA-MBZUAI/XReal.
With the rise of social platforms, protecting privacy has become an important issue. Privacy object detection aims to accurately locate private objects in images. It is the foundation of safeguarding individuals' privacy rights and ensuring responsible data handling practices in the digital age. Since privacy of object is not shift-invariant, the essence of the privacy object detection task is inferring object privacy based on scene information. However, privacy object detection has long been studied as a subproblem of common object detection tasks. Therefore, existing methods suffer from serious deficiencies in accuracy, generalization, and interpretability. Moreover, creating large-scale privacy datasets is difficult due to legal constraints and existing privacy datasets lack label granularity. The granularity of existing privacy detection methods remains limited to the image level. To address the above two issues, we introduce two benchmark datasets for object-level privacy detection and propose SHAN, Scene Heterogeneous graph Attention Network, a model constructs a scene heterogeneous graph from an image and utilizes self-attention mechanisms for scene inference to obtain object privacy. Through experiments, we demonstrated that SHAN performs excellently in privacy object detection tasks, with all metrics surpassing those of the baseline model.
Robot navigation under visual corruption presents a formidable challenge. To address this, we propose a Test-time Adaptation (TTA) method, named as TTA-Nav, for point-goal navigation under visual corruptions. Our "plug-and-play" method incorporates a top-down decoder to a pre-trained navigation model. Firstly, the pre-trained navigation model gets a corrupted image and extracts features. Secondly, the top-down decoder produces the reconstruction given the high-level features extracted by the pre-trained model. Then, it feeds the reconstruction of a corrupted image back to the pre-trained model. Finally, the pre-trained model does forward pass again to output action. Despite being trained solely on clean images, the top-down decoder can reconstruct cleaner images from corrupted ones without the need for gradient-based adaptation. The pre-trained navigation model with our top-down decoder significantly enhances navigation performance across almost all visual corruptions in our benchmarks. Our method improves the success rate of point-goal navigation from the state-of-the-art result of 46% to 94% on the most severe corruption. This suggests its potential for broader application in robotic visual navigation. Project page: https://sites.google.com/view/tta-nav
Prior-based methods for low-light image enhancement often face challenges in extracting available prior information from dim images. To overcome this limitation, we introduce a simple yet effective Retinex model with the proposed edge extraction prior. More specifically, we design an edge extraction network to capture the fine edge features from the low-light image directly. Building upon the Retinex theory, we decompose the low-light image into its illumination and reflectance components and introduce an edge-guided Retinex model for enhancing low-light images. To solve the proposed model, we propose a novel inertial Bregman alternating linearized minimization algorithm. This algorithm addresses the optimization problem associated with the edge-guided Retinex model, enabling effective enhancement of low-light images. Through rigorous theoretical analysis, we establish the convergence properties of the algorithm. Besides, we prove that the proposed algorithm converges to a stationary point of the problem through nonconvex optimization theory. Furthermore, extensive experiments are conducted on multiple real-world low-light image datasets to demonstrate the efficiency and superiority of the proposed scheme.
Current rock engineering design in drill and blast tunnelling primarily relies on engineers' observational assessments. Measure While Drilling (MWD) data, a high-resolution sensor dataset collected during tunnel excavation, is underutilised, mainly serving for geological visualisation. This study aims to automate the translation of MWD data into actionable metrics for rock engineering. It seeks to link data to specific engineering actions, thus providing critical decision support for geological challenges ahead of the tunnel face. Leveraging a large and geologically diverse dataset of 500,000 drillholes from 15 tunnels, the research introduces models for accurate rock mass quality classification in a real-world tunnelling context. Both conventional machine learning and image-based deep learning are explored to classify MWD data into Q-classes and Q-values, examples of metrics describing the stability of the rock mass, using both tabular and image data. The results indicate that the K-nearest neighbours algorithm in an ensemble with tree-based models using tabular data, effectively classifies rock mass quality. It achieves a cross-validated balanced accuracy of 0.86 in classifying rock mass into the Q-classes A, B, C, D, E1, E2, and 0.95 for a binary classification with E versus the rest. Classification using a CNN with MWD-images for each blasting round resulted in a balanced accuracy of 0.82 for binary classification. Regressing the Q-value from tabular MWD-data achieved cross-validated R2 and MSE scores of 0.80 and 0.18 for a similar ensemble model as in classification. High performance in regression and classification boosts confidence in automated rock mass assessment. Applying advanced modelling on a unique dataset demonstrates MWD data's value in improving rock mass classification accuracy and advancing data-driven rock engineering design, reducing manual intervention.