Style Generation in Robot Calligraphy with Deep Generative Adversarial Networks

Robot calligraphy is an emerging exploration of artificial intelligence in the fields of art and education. Traditional calligraphy generation researches mainly focus on methods such as tool-based image processing, generative models, and style transfer. Unlike the English alphabet, the number of Chinese characters is tens of thousands, which leads to difficulties in the generation of a style consistent Chinese calligraphic font with over 6000 characters. Due to the lack of high-quality data sets, formal definitions of calligraphy knowledge, and scientific art evaluation methods, The results generated are frequently of low quality and falls short of professional-level requirements. To address the above problem, this paper proposes an automatic calligraphy generation model based on deep generative adversarial networks (deepGAN) that can generate style calligraphy fonts with professional standards. The key highlights of the proposed method include: (1) The datasets use a high-precision calligraphy synthesis method to ensure its high quality and sufficient quantity; (2) Professional calligraphers are invited to conduct a series of Turing tests to evaluate the gap between model generation results and human artistic level; (3) Experimental results indicate that the proposed model is the state-of-the-art among current calligraphy generation methods. The Turing tests and similarity evaluations validate the effectiveness of the proposed method.

PathoDuet: Foundation Models for Pathological Slide Analysis of H&E and IHC Stains

Large amounts of digitized histopathological data display a promising future for developing pathological foundation models via self-supervised learning methods. Foundation models pretrained with these methods serve as a good basis for downstream tasks. However, the gap between natural and histopathological images hinders the direct application of existing methods. In this work, we present PathoDuet, a series of pretrained models on histopathological images, and a new self-supervised learning framework in histopathology. The framework is featured by a newly-introduced pretext token and later task raisers to explicitly utilize certain relations between images, like multiple magnifications and multiple stains. Based on this, two pretext tasks, cross-scale positioning and cross-stain transferring, are designed to pretrain the model on Hematoxylin and Eosin (H\&E) images and transfer the model to immunohistochemistry (IHC) images, respectively. To validate the efficacy of our models, we evaluate the performance over a wide variety of downstream tasks, including patch-level colorectal cancer subtyping and whole slide image (WSI)-level classification in H\&E field, together with expression level prediction of IHC marker and tumor identification in IHC field. The experimental results show the superiority of our models over most tasks and the efficacy of proposed pretext tasks. The codes and models are available at https://github.com/openmedlab/PathoDuet.

Structural Information Guided Multimodal Pre-training for Vehicle-centric Perception

Understanding vehicles in images is important for various applications such as intelligent transportation and self-driving system. Existing vehicle-centric works typically pre-train models on large-scale classification datasets and then fine-tune them for specific downstream tasks. However, they neglect the specific characteristics of vehicle perception in different tasks and might thus lead to sub-optimal performance. To address this issue, we propose a novel vehicle-centric pre-training framework called VehicleMAE, which incorporates the structural information including the spatial structure from vehicle profile information and the semantic structure from informative high-level natural language descriptions for effective masked vehicle appearance reconstruction. To be specific, we explicitly extract the sketch lines of vehicles as a form of the spatial structure to guide vehicle reconstruction. The more comprehensive knowledge distilled from the CLIP big model based on the similarity between the paired/unpaired vehicle image-text sample is further taken into consideration to help achieve a better understanding of vehicles. A large-scale dataset is built to pre-train our model, termed Autobot1M, which contains about 1M vehicle images and 12693 text information. Extensive experiments on four vehicle-based downstream tasks fully validated the effectiveness of our VehicleMAE. The source code and pre-trained models will be released at https://github.com/Event-AHU/VehicleMAE.

SegRap2023: A Benchmark of Organs-at-Risk and Gross Tumor Volume Segmentation for Radiotherapy Planning of Nasopharyngeal Carcinoma

Radiation therapy is a primary and effective NasoPharyngeal Carcinoma (NPC) treatment strategy. The precise delineation of Gross Tumor Volumes (GTVs) and Organs-At-Risk (OARs) is crucial in radiation treatment, directly impacting patient prognosis. Previously, the delineation of GTVs and OARs was performed by experienced radiation oncologists. Recently, deep learning has achieved promising results in many medical image segmentation tasks. However, for NPC OARs and GTVs segmentation, few public datasets are available for model development and evaluation. To alleviate this problem, the SegRap2023 challenge was organized in conjunction with MICCAI2023 and presented a large-scale benchmark for OAR and GTV segmentation with 400 Computed Tomography (CT) scans from 200 NPC patients, each with a pair of pre-aligned non-contrast and contrast-enhanced CT scans. The challenge's goal was to segment 45 OARs and 2 GTVs from the paired CT scans. In this paper, we detail the challenge and analyze the solutions of all participants. The average Dice similarity coefficient scores for all submissions ranged from 76.68\% to 86.70\%, and 70.42\% to 73.44\% for OARs and GTVs, respectively. We conclude that the segmentation of large-size OARs is well-addressed, and more efforts are needed for GTVs and small-size or thin-structure OARs. The benchmark will remain publicly available here: https://segrap2023.grand-challenge.org

Privacy-Aware Document Visual Question Answering

Document Visual Question Answering (DocVQA) is a fast growing branch of document understanding. Despite the fact that documents contain sensitive or copyrighted information, none of the current DocVQA methods offers strong privacy guarantees. In this work, we explore privacy in the domain of DocVQA for the first time. We highlight privacy issues in state of the art multi-modal LLM models used for DocVQA, and explore possible solutions. Specifically, we focus on the invoice processing use case as a realistic, widely used scenario for document understanding, and propose a large scale DocVQA dataset comprising invoice documents and associated questions and answers. We employ a federated learning scheme, that reflects the real-life distribution of documents in different businesses, and we explore the use case where the ID of the invoice issuer is the sensitive information to be protected. We demonstrate that non-private models tend to memorise, behaviour that can lead to exposing private information. We then evaluate baseline training schemes employing federated learning and differential privacy in this multi-modal scenario, where the sensitive information might be exposed through any of the two input modalities: vision (document image) or language (OCR tokens). Finally, we design an attack exploiting the memorisation effect of the model, and demonstrate its effectiveness in probing different DocVQA models.

Medical Image Segmentation with Domain Adaptation: A Survey

Deep learning (DL) has shown remarkable success in various medical imaging data analysis applications. However, it remains challenging for DL models to achieve good generalization, especially when the training and testing datasets are collected at sites with different scanners, due to domain shift caused by differences in data distributions. Domain adaptation has emerged as an effective means to address this challenge by mitigating domain gaps in medical imaging applications. In this review, we specifically focus on domain adaptation approaches for DL-based medical image segmentation. We first present the motivation and background knowledge underlying domain adaptations, then provide a comprehensive review of domain adaptation applications in medical image segmentations, and finally discuss the challenges, limitations, and future research trends in the field to promote the methodology development of domain adaptation in the context of medical image segmentation. Our goal was to provide researchers with up-to-date references on the applications of domain adaptation in medical image segmentation studies.

Diagonal Hierarchical Consistency Learning for Semi-supervised Medical Image Segmentation

Medical image segmentation, which is essential for many clinical applications, has achieved almost human-level performance via data-driven deep learning techniques. Nevertheless, its performance is predicated on the costly process of manually annotating a large amount of medical images. To this end, we propose a novel framework for robust semi-supervised medical image segmentation using diagonal hierarchical consistency (DiHC-Net). First, it is composed of multiple sub-models with identical multi-scale architecture but with distinct sub-layers, such as up-sampling and normalisation layers. Second, a novel diagonal hierarchical consistency is enforced between one model's intermediate and final prediction and other models' soft pseudo labels in a diagonal hierarchical fashion. Experimental results verify the efficacy of our simple framework, outperforming all previous approaches on public Left Atrium (LA) dataset.

The Perception-Robustness Tradeoff in Deterministic Image Restoration

We study the behavior of deterministic methods for solving inverse problems in imaging. These methods are commonly designed to achieve two goals: (1) attaining high perceptual quality, and (2) generating reconstructions that are consistent with the measurements. We provide a rigorous proof that the better a predictor satisfies these two requirements, the larger its Lipschitz constant must be, regardless of the nature of the degradation involved. In particular, to approach perfect perceptual quality and perfect consistency, the Lipschitz constant of the model must grow to infinity. This implies that such methods are necessarily more susceptible to adversarial attacks. We demonstrate our theory on single image super-resolution algorithms, addressing both noisy and noiseless settings. We also show how this undesired behavior can be leveraged to explore the posterior distribution, thereby allowing the deterministic model to imitate stochastic methods.

Quilt-LLaVA: Visual Instruction Tuning by Extracting Localized Narratives from Open-Source Histopathology Videos

The gigapixel scale of whole slide images (WSIs) poses a challenge for histopathology multi-modal chatbots, requiring a global WSI analysis for diagnosis, compounding evidence from different WSI patches. Current visual instruction datasets, generated through large language models, focus on creating question/answer pairs for individual image patches, which may lack diagnostic capacity on their own in histopathology, further complicated by the absence of spatial grounding in histopathology image captions. To bridge this gap, we introduce Quilt-Instruct, a large-scale dataset of 107,131 histopathology-specific instruction question/answer pairs, that is collected by leveraging educational histopathology videos from YouTube, which provides spatial localization of captions by automatically extracting narrators' cursor movements. In addition, we provide contextual reasoning by extracting diagnosis and supporting facts from the entire video content to guide the extrapolative reasoning of GPT-4. Using Quilt-Instruct, we train Quilt-LLaVA, which can reason beyond the given single image patch, enabling diagnostic reasoning and the capability of spatial awareness. To evaluate Quilt-LLaVA, we propose a comprehensive evaluation dataset created from 985 images and 1283 human-generated question-answers. We also thoroughly evaluate Quilt-LLaVA using public histopathology datasets, where Quilt-LLaVA significantly outperforms SOTA by over 10% on relative GPT-4 score and 4% and 9% on open and closed set VQA. Our code, data, and model are publicly available at quilt-llava.github.io.

Gen2Det: Generate to Detect

Recently diffusion models have shown improvement in synthetic image quality as well as better control in generation. We motivate and present Gen2Det, a simple modular pipeline to create synthetic training data for object detection for free by leveraging state-of-the-art grounded image generation methods. Unlike existing works which generate individual object instances, require identifying foreground followed by pasting on other images, we simplify to directly generating scene-centric images. In addition to the synthetic data, Gen2Det also proposes a suite of techniques to best utilize the generated data, including image-level filtering, instance-level filtering, and better training recipe to account for imperfections in the generation. Using Gen2Det, we show healthy improvements on object detection and segmentation tasks under various settings and agnostic to detection methods. In the long-tailed detection setting on LVIS, Gen2Det improves the performance on rare categories by a large margin while also significantly improving the performance on other categories, e.g. we see an improvement of 2.13 Box AP and 1.84 Mask AP over just training on real data on LVIS with Mask R-CNN. In the low-data regime setting on COCO, Gen2Det consistently improves both Box and Mask AP by 2.27 and 1.85 points. In the most general detection setting, Gen2Det still demonstrates robust performance gains, e.g. it improves the Box and Mask AP on COCO by 0.45 and 0.32 points.