DESAT: an SSW tool for SDO/AIA image de-saturation

Saturation affects a significant rate of images recorded by the Atmospheric Imaging Assembly on the Solar Dynamics Observatory. This paper describes a computational method and a technological pipeline for the de-saturation of such images, based on several mathematical ingredients like Expectation Maximization, image correlation and interpolation. An analysis of the computational properties and demands of the pipeline, together with an assessment of its reliability are performed against a set of data recorded from the Feburary 25 2014 flaring event.

ATIS + SpiNNaker: a Fully Event-based Visual Tracking Demonstration

The Asynchronous Time-based Image Sensor (ATIS) and the Spiking Neural Network Architecture (SpiNNaker) are both neuromorphic technologies that "unconventionally" use binary spikes to represent information. The ATIS produces spikes to represent the change in light falling on the sensor, and the SpiNNaker is a massively parallel computing platform that asynchronously sends spikes between cores for processing. In this demonstration we show these two hardware used together to perform a visual tracking task. We aim to show the hardware and software architecture that integrates the ATIS and SpiNNaker together in a robot middle-ware that makes processing agnostic to the platform (CPU or SpiNNaker). We also aim to describe the algorithm, why it is suitable for the "unconventional" sensor and processing platform including the advantages as well as challenges faced.

Deep Optics for Monocular Depth Estimation and 3D Object Detection

Depth estimation and 3D object detection are critical for scene understanding but remain challenging to perform with a single image due to the loss of 3D information during image capture. Recent models using deep neural networks have improved monocular depth estimation performance, but there is still difficulty in predicting absolute depth and generalizing outside a standard dataset. Here we introduce the paradigm of deep optics, i.e. end-to-end design of optics and image processing, to the monocular depth estimation problem, using coded defocus blur as an additional depth cue to be decoded by a neural network. We evaluate several optical coding strategies along with an end-to-end optimization scheme for depth estimation on three datasets, including NYU Depth v2 and KITTI. We find an optimized freeform lens design yields the best results, but chromatic aberration from a singlet lens offers significantly improved performance as well. We build a physical prototype and validate that chromatic aberrations improve depth estimation on real-world results. In addition, we train object detection networks on the KITTI dataset and show that the lens optimized for depth estimation also results in improved 3D object detection performance.

ADN: Artifact Disentanglement Network for Unsupervised Metal Artifact Reduction

Current deep neural network based approaches to computed tomography (CT) metal artifact reduction (MAR) are supervised methods that rely on synthesized metal artifacts for training. However, as synthesized data may not accurately simulate the underlying physical mechanisms of CT imaging, the supervised methods often generalize poorly to clinical applications. To address this problem, we propose, to the best of our knowledge, the first unsupervised learning approach to MAR. Specifically, we introduce a novel artifact disentanglement network that disentangles the metal artifacts from CT images in the latent space. It supports different forms of generations (artifact reduction, artifact transfer, and self-reconstruction, etc.) with specialized loss functions to obviate the need for supervision with synthesized data. Extensive experiments show that when applied to a synthesized dataset, our method addresses metal artifacts significantly better than the existing unsupervised models designed for natural image-to-image translation problems, and achieves comparable performance to existing supervised models for MAR. When applied to clinical datasets, our method demonstrates better generalization ability over the supervised models. The source code of this paper is publicly available at https://github.com/liaohaofu/adn.

Breast lesion segmentation in ultrasound images with limited annotated data

Ultrasound (US) is one of the most commonly used imaging modalities in both diagnosis and surgical interventions due to its low-cost, safety, and non-invasive characteristic. US image segmentation is currently a unique challenge because of the presence of speckle noise. As manual segmentation requires considerable efforts and time, the development of automatic segmentation algorithms has attracted researchers attention. Although recent methodologies based on convolutional neural networks have shown promising performances, their success relies on the availability of a large number of training data, which is prohibitively difficult for many applications. Therefore, in this study we propose the use of simulated US images and natural images as auxiliary datasets in order to pre-train our segmentation network, and then to fine-tune with limited in vivo data. We show that with as little as 19 in vivo images, fine-tuning the pre-trained network improves the dice score by 21% compared to training from scratch. We also demonstrate that if the same number of natural and simulation US images is available, pre-training on simulation data is preferable.

Computer Aided Detection for Pulmonary Embolism Challenge (CAD-PE)

Rationale: Computer aided detection (CAD) algorithms for Pulmonary Embolism (PE) algorithms have been shown to increase radiologists' sensitivity with a small increase in specificity. However, CAD for PE has not been adopted into clinical practice, likely because of the high number of false positives current CAD software produces. Objective: To generate a database of annotated computed tomography pulmonary angiographies, use it to compare the sensitivity and false positive rate of current algorithms and to develop new methods that improve such metrics. Methods: 91 Computed tomography pulmonary angiography scans were annotated by at least one radiologist by segmenting all pulmonary emboli visible on the study. 20 annotated CTPAs were open to the public in the form of a medical image analysis challenge. 20 more were kept for evaluation purposes. 51 were made available post-challenge. 8 submissions, 6 of them novel, were evaluated on the 20 evaluation CTPAs. Performance was measured as per embolus sensitivity vs. false positives per scan curve. Results: The best algorithms achieved a per-embolus sensitivity of 75% at 2 false positives per scan (fps) or of 70% at 1 fps, outperforming the state of the art. Deep learning approaches outperformed traditional machine learning ones, and their performance improved with the number of training cases. Significance: Through this work and challenge we have improved the state-of-the art of computer aided detection algorithms for pulmonary embolism. An open database and an evaluation benchmark for such algorithms have been generated, easing the development of further improvements. Implications on clinical practice will need further research.

Accelerated Motion-Aware MR Imaging via Motion Prediction from K-Space Center

Motion has been a challenge for magnetic resonance (MR) imaging ever since the MR has been invented. Especially in volumetric imaging of thoracic and abdominal organs, motion-awareness is essential for reducing motion artifacts in the final image. A recently proposed MR imaging approach copes with motion by observing the motion patterns during the acquisition. Repetitive scanning of the k-space center region enables the extraction of the patient motion while acquiring the remaining part of the k-space. Due to highly redundant measurements of the center, the required scanning time of over 11 min and the reconstruction time of 2 h exceed clinical applicability though. We propose an accelerated motion-aware MR imaging method where the motion is inferred from small-sized k-space center patches and an initial training phase during which the characteristic movements are modeled. Thereby, acquisition times are reduced by a factor of almost 2 and reconstruction times by two orders of magnitude. Moreover, we improve the existing motion-aware approach with a systematic temporal shift correction to achieve a sharper image reconstruction. We tested our method on 12 volunteers and scanned their lungs and abdomen under free breathing. We achieved equivalent to higher reconstruction quality using the motion-prediction compared to the slower existing approach.

Online Normalization for Training Neural Networks

Online Normalization is a new technique for normalizing the hidden activations of a neural network. Like Batch Normalization, it normalizes the sample dimension. While Online Normalization does not use batches, it is as accurate as Batch Normalization. We resolve a theoretical limitation of Batch Normalization by introducing an unbiased technique for computing the gradient of normalized activations. Online Normalization works with automatic differentiation by adding statistical normalization as a primitive. This technique can be used in cases not covered by some other normalizers, such as recurrent networks, fully connected networks, and networks with activation memory requirements prohibitive for batching. We show its applications to image classification, image segmentation, and language modeling. We present formal proofs and experimental results on ImageNet, CIFAR, and PTB datasets.

Equivariant Transformer Networks

How can prior knowledge on the transformation invariances of a domain be incorporated into the architecture of a neural network? We propose Equivariant Transformers (ETs), a family of differentiable image-to-image mappings that improve the robustness of models towards pre-defined continuous transformation groups. Through the use of specially-derived canonical coordinate systems, ETs incorporate functions that are equivariant by construction with respect to these transformations. We show empirically that ETs can be flexibly composed to improve model robustness towards more complicated transformation groups in several parameters. On a real-world image classification task, ETs improve the sample efficiency of ResNet classifiers, achieving relative improvements in error rate of up to 15% in the limited data regime while increasing model parameter count by less than 1%.

Attend To Count: Crowd Counting with Adaptive Capacity Multi-scale CNNs

Crowd counting is a challenging task due to the large variations in crowd distributions. Previous methods tend to tackle the whole image with a single fixed structure, which is unable to handle diverse complicated scenes with different crowd densities. Hence, we propose the Adaptive Capacity Multi-scale convolutional neural networks (ACM-CNN), a novel crowd counting approach which can assign different capacities to different portions of the input. The intuition is that the model should focus on important regions of the input image and optimize its capacity allocation conditioning on the crowd intensive degree. ACM-CNN consists of three types of modules: a coarse network, a fine network, and a smooth network. The coarse network is used to explore the areas that need to be focused via count attention mechanism, and generate a rough feature map. Then the fine network processes the areas of interest into a fine feature map. To alleviate the sense of division caused by fusion, the smooth network is designed to combine two feature maps organically to produce high-quality density maps. Extensive experiments are conducted on five mainstream datasets. The results demonstrate the effectiveness of the proposed model for both density estimation and crowd counting tasks.