Recently DCNN (Deep Convolutional Neural Network) has been advocated as a general and promising modelling approach for neural object representation in primate inferotemporal cortex. In this work, we show that some inherent non-uniqueness problem exists in the DCNN-based modelling of image object representations. This non-uniqueness phenomenon reveals to some extent the theoretical limitation of this general modelling approach, and invites due attention to be taken in practice.
In the last decade, machine learning and artificial intelligence applications have received a significant boost in performance and attention in both academic research and industry. The success behind most of the recent state-of-the-art methods can be attributed to the latest developments in deep learning. When applied to various scientific domains that are concerned with the processing of non-tabular data, for example, image or text, deep learning has been shown to outperform not only conventional machine learning but also highly specialized tools developed by domain experts. This review aims to summarize AI-based research for GPCR bioactive ligand discovery with a particular focus on the most recent achievements and research trends. To make this article accessible to a broad audience of computational scientists, we provide instructive explanations of the underlying methodology, including overviews of the most commonly used deep learning architectures and feature representations of molecular data. We highlight the latest AI-based research that has led to the successful discovery of GPCR bioactive ligands. However, an equal focus of this review is on the discussion of machine learning-based technology that has been applied to ligand discovery in general and has the potential to pave the way for successful GPCR bioactive ligand discovery in the future. This review concludes with a brief outlook highlighting the recent research trends in deep learning, such as active learning and semi-supervised learning, which have great potential for advancing bioactive ligand discovery.
A robust evaluation metric has a profound impact on the development of text generation systems. A desirable metric compares system output against references based on their semantics rather than surface forms. In this paper we investigate strategies to encode system and reference texts to devise a metric that shows a high correlation with human judgment of text quality. We validate our new metric, namely MoverScore, on a number of text generation tasks including summarization, machine translation, image captioning, and data-to-text generation, where the outputs are produced by a variety of neural and non-neural systems. Our findings suggest that metrics combining contextualized representations with a distance measure perform the best. Such metrics also demonstrate strong generalization capability across tasks. For ease-of-use we make our metrics available as web service.
Recent neural style transfer frameworks have obtained astonishing visual quality and flexibility in Single-style Transfer (SST), but little attention has been paid to Multi-style Transfer (MST) which refers to simultaneously transferring multiple styles to the same image. Compared to SST, MST has the potential to create more diverse and visually pleasing stylization results. In this paper, we propose the first MST framework to automatically incorporate multiple styles into one result based on regional semantics. We first improve the existing SST backbone network by introducing a novel multi-level feature fusion module and a patch attention module to achieve better semantic correspondences and preserve richer style details. For MST, we designed a conceptually simple yet effective region-based style fusion module to insert into the backbone. It assigns corresponding styles to content regions based on semantic matching, and then seamlessly combines multiple styles together. Comprehensive evaluations demonstrate that our framework outperforms existing works of SST and MST.
Nowadays, Deep learning techniques show dramatic performance on computer vision area, and they even outperform human. But it is also vulnerable to some small perturbation called an adversarial attack. This is a problem combined with the safety of artificial intelligence, which has recently been studied a lot. These attacks have shown that they can fool models of image classification, semantic segmentation, and object detection. We point out this attack can be protected by denoise autoencoder, which is used for denoising the perturbation and restoring the original images. We experiment with various noise distributions and verify the effect of denoise autoencoder against adversarial attack in semantic segmentation.
Promising results have been achieved in image classification problems by exploiting the discriminative power of sparse representations for classification (SRC). Recently, it has been shown that the use of \emph{class-specific} spike-and-slab priors in conjunction with the class-specific dictionaries from SRC is particularly effective in low training scenarios. As a logical extension, we build on this framework for multitask scenarios, wherein multiple representations of the same physical phenomena are available. We experimentally demonstrate the benefits of mining joint information from different camera views for multi-view face recognition.
Recurrent Neural Networks (RNNs) yield attractive properties for constructing Intrusion Detection Systems (IDSs) for network data. With the rise of ubiquitous Machine Learning (ML) systems, malicious actors have been catching up quickly to find new ways to exploit ML vulnerabilities for profit. Recently developed adversarial ML techniques focus on computer vision and their applicability to network traffic is not straightforward: Network packets expose fewer features than an image, are sequential and impose several constraints on their features. We show that despite these completely different characteristics, adversarial samples can be generated reliably for RNNs. To understand a classifier's potential for misclassification, we extend existing explainability techniques and propose new ones, suitable particularly for sequential data. Applying them shows that already the first packets of a communication flow are of crucial importance and are likely to be targeted by attackers. Feature importance methods show that even relatively unimportant features can be effectively abused to generate adversarial samples. Since traditional evaluation metrics such as accuracy are not sufficient for quantifying the adversarial threat, we propose the Adversarial Robustness Score (ARS) for comparing IDSs, capturing a common notion of adversarial robustness, and show that an adversarial training procedure can significantly and successfully reduce the attack surface.
Given the ability to directly manipulate image pixels in the digital input space, an adversary can easily generate imperceptible perturbations to fool a Deep Neural Network (DNN) image classifier, as demonstrated in prior work. In this work, we propose ShapeShifter, an attack that tackles the more challenging problem of crafting physical adversarial perturbations to fool image-based object detectors like Faster R-CNN. Attacking an object detector is more difficult than attacking an image classifier, as it needs to mislead the classification results in multiple bounding boxes with different scales. Extending the digital attack to the physical world adds another layer of difficulty, because it requires the perturbation to be robust enough to survive real-world distortions due to different viewing distances and angles, lighting conditions, and camera limitations. We show that the Expectation over Transformation technique, which was originally proposed to enhance the robustness of adversarial perturbations in image classification, can be successfully adapted to the object detection setting. ShapeShifter can generate adversarially perturbed stop signs that are consistently mis-detected by Faster R-CNN as other objects, posing a potential threat to autonomous vehicles and other safety-critical computer vision systems.
We propose Axial Transformers, a self-attention-based autoregressive model for images and other data organized as high dimensional tensors. Existing autoregressive models either suffer from excessively large computational resource requirements for high dimensional data, or make compromises in terms of distribution expressiveness or ease of implementation in order to decrease resource requirements. Our architecture, by contrast, maintains both full expressiveness over joint distributions over data and ease of implementation with standard deep learning frameworks, while requiring reasonable memory and computation and achieving state-of-the-art results on standard generative modeling benchmarks. Our models are based on axial attention, a simple generalization of self-attention that naturally aligns with the multiple dimensions of the tensors in both the encoding and the decoding settings. Notably the proposed structure of the layers allows for the vast majority of the context to be computed in parallel during decoding without introducing any independence assumptions. This semi-parallel structure goes a long way to making decoding from even a very large Axial Transformer broadly applicable. We demonstrate state-of-the-art results for the Axial Transformer on the ImageNet-32 and ImageNet-64 image benchmarks as well as on the BAIR Robotic Pushing video benchmark. We open source the implementation of Axial Transformers.
Even with the growing interest in problems at the intersection of Computer Vision and Natural Language, grounding (i.e. identifying) the components of a structured description in an image still remains a challenging task. This contribution aims to propose a model which learns grounding by reconstructing the visual features for the Multi-modal translation task. Previous works have partially investigated standard approaches such as regression methods to approximate the reconstruction of a visual input. In this paper, we propose a different and novel approach which learns grounding by adversarial feedback. To do so, we modulate our network following the recent promising adversarial architectures and evaluate how the adversarial response from a visual reconstruction as an auxiliary task helps the model in its learning. We report the highest scores in term of BLEU and METEOR metrics on the different datasets.