Degenerative spinal pathologies are highly prevalent among the elderly population. Timely diagnosis of osteoporotic fractures and other degenerative deformities facilitates proactive measures to mitigate the risk of severe back pain and disability. In this study, we specifically explore the use of shape auto-encoders for vertebrae, taking advantage of advancements in automated multi-label segmentation and the availability of large datasets for unsupervised learning. Our shape auto-encoders are trained on a large set of vertebrae surface patches, leveraging the vast amount of available data for vertebra segmentation. This addresses the label scarcity problem faced when learning shape information of vertebrae from image intensities. Based on the learned shape features we train an MLP to detect vertebral body fractures. Using segmentation masks that were automatically generated using the TotalSegmentator, our proposed method achieves an AUC of 0.901 on the VerSe19 testset. This outperforms image-based and surface-based end-to-end trained models. Additionally, our results demonstrate that pre-training the models in an unsupervised manner enhances geometric methods like PointNet and DGCNN. Our findings emphasise the advantages of explicitly learning shape features for diagnosing osteoporotic vertebrae fractures. This approach improves the reliability of classification results and reduces the need for annotated labels. This study provides novel insights into the effectiveness of various encoder-decoder models for shape analysis of vertebrae and proposes a new decoder architecture: the point-based shape decoder.
Whole-slide image (WSI) analysis plays a crucial role in cancer diagnosis and treatment. In addressing the demands of this critical task, self-supervised learning (SSL) methods have emerged as a valuable resource, leveraging their efficiency in circumventing the need for a large number of annotations, which can be both costly and time-consuming to deploy supervised methods. Nevertheless, patch-wise representation may exhibit instability in performance, primarily due to class imbalances stemming from patch selection within WSIs. In this paper, we introduce Nearby Patch Contrastive Learning (NearbyPatchCL), a novel self-supervised learning method that leverages nearby patches as positive samples and a decoupled contrastive loss for robust representation learning. Our method demonstrates a tangible enhancement in performance for downstream tasks involving patch-level multi-class classification. Additionally, we curate a new dataset derived from WSIs sourced from the Canine Cutaneous Cancer Histology, thus establishing a benchmark for the rigorous evaluation of patch-level multi-class classification methodologies. Intensive experiments show that our method significantly outperforms the supervised baseline and state-of-the-art SSL methods with top-1 classification accuracy of 87.56%. Our method also achieves comparable results while utilizing a mere 1% of labeled data, a stark contrast to the 100% labeled data requirement of other approaches. Source code: https://github.com/nvtien457/NearbyPatchCL
Diffusion models, such as Stable Diffusion (SD), offer the ability to generate high-resolution images with diverse features, but they come at a significant computational and memory cost. In classifier-free guided diffusion models, prolonged inference times are attributed to the necessity of computing two separate diffusion models at each denoising step. Recent work has shown promise in improving inference time through distillation techniques, teaching the model to perform similar denoising steps with reduced computations. However, the application of distillation introduces additional memory overhead to these already resource-intensive diffusion models, making it less practical. To address these challenges, our research explores a novel approach that combines Low-Rank Adaptation (LoRA) with model distillation to efficiently compress diffusion models. This approach not only reduces inference time but also mitigates memory overhead, and notably decreases memory consumption even before applying distillation. The results are remarkable, featuring a significant reduction in inference time due to the distillation process and a substantial 50% reduction in memory consumption. Our examination of the generated images underscores that the incorporation of LoRA-enhanced distillation maintains image quality and alignment with the provided prompts. In summary, while conventional distillation tends to increase memory consumption, LoRA-enhanced distillation offers optimization without any trade-offs or compromises in quality.
Photoacoustic Microscopy (PAM) images integrating the advantages of optical contrast and acoustic resolution have been widely used in brain studies. However, there exists a trade-off between scanning speed and image resolution. Compared with traditional raster scanning, rotational scanning provides good opportunities for fast PAM imaging by optimizing the scanning mechanism. Recently, there is a trend to incorporate deep learning into the scanning process to further increase the scanning speed.Yet, most such attempts are performed for raster scanning while those for rotational scanning are relatively rare. In this study, we propose a novel and well-performing super-resolution framework for rotational scanning-based PAM imaging. To eliminate adjacent rows' displacements due to subject motion or high-frequency scanning distortion,we introduce a registration module across odd and even rows in the preprocessing and incorporate displacement degradation in the training. Besides, gradient-based patch selection is proposed to increase the probability of blood vessel patches being selected for training. A Transformer-based network with a global receptive field is applied for better performance. Experimental results on both synthetic and real datasets demonstrate the effectiveness and generalizability of our proposed framework for rotationally scanned PAM images'super-resolution, both quantitatively and qualitatively. Code is available at https://github.com/11710615/PAMSR.git.
With the explosive 3D data growth, the urgency of utilizing zero-shot learning to facilitate data labeling becomes evident. Recently, the methods via transferring Contrastive Language-Image Pre-training (CLIP) to 3D vision have made great progress in the 3D zero-shot classification task. However, these methods primarily focus on aligned pose 3D objects (ap-3os), overlooking the recognition of 3D objects with open poses (op-3os) typically encountered in real-world scenarios, such as an overturned chair or a lying teddy bear. To this end, we propose a more challenging benchmark for 3D open-pose zero-shot classification. Echoing our benchmark, we design a concise angle-refinement mechanism that automatically optimizes one ideal pose as well as classifies these op-3os. Furthermore, we make a first attempt to bridge 2D pre-trained diffusion model as a classifer to 3D zero-shot classification without any additional training. Such 2D diffusion to 3D objects proves vital in improving zero-shot classification for both ap-3os and op-3os. Our model notably improves by 3.5% and 15.8% on ModelNet10$^{\ddag}$ and McGill$^{\ddag}$ open pose benchmarks, respectively, and surpasses the current state-of-the-art by 6.8% on the aligned pose ModelNet10, affirming diffusion's efficacy in 3D zero-shot tasks.
Text-conditioned image editing has succeeded in various types of editing based on a diffusion framework. Unfortunately, this success did not carry over to a video, which continues to be challenging. Existing video editing systems are still limited to rigid-type editing such as style transfer and object overlay. To this end, this paper proposes Neutral Editing (NeuEdit) framework to enable complex non-rigid editing by changing the motion of a person/object in a video, which has never been attempted before. NeuEdit introduces a concept of `neutralization' that enhances a tuning-editing process of diffusion-based editing systems in a model-agnostic manner by leveraging input video and text without any other auxiliary aids (e.g., visual masks, video captions). Extensive experiments on numerous videos demonstrate adaptability and effectiveness of the NeuEdit framework. The website of our work is available here: https://neuedit.github.io
Detecting objects in low-light scenarios presents a persistent challenge, as detectors trained on well-lit data exhibit significant performance degradation on low-light data due to the low visibility. Previous methods mitigate this issue by investigating image enhancement or object detection techniques using low-light image datasets. However, the progress is impeded by the inherent difficulties associated with collecting and annotating low-light images. To address this challenge, we propose to boost low-light object detection with zero-shot day-night domain adaptation, which aims to generalize a detector from well-lit scenarios to low-light ones without requiring real low-light data. We first design a reflectance representation learning module to learn Retinex-based illumination invariance in images with a carefully designed illumination invariance reinforcement strategy. Next, an interchange-redecomposition-coherence procedure is introduced to improve over the vanilla Retinex image decomposition process by performing two sequential image decompositions and introducing a redecomposition cohering loss. Extensive experiments on ExDark, DARK FACE and CODaN datasets show strong low-light generalizability of our method.
Medical Image-to-image translation is a key task in computer vision and generative artificial intelligence, and it is highly applicable to medical image analysis. GAN-based methods are the mainstream image translation methods, but they often ignore the variation and distribution of images in the frequency domain, or only take simple measures to align high-frequency information, which can lead to distortion and low quality of the generated images. To solve these problems, we propose a novel method called frequency domain decomposition translation (FDDT). This method decomposes the original image into a high-frequency component and a low-frequency component, with the high-frequency component containing the details and identity information, and the low-frequency component containing the style information. Next, the high-frequency and low-frequency components of the transformed image are aligned with the transformed results of the high-frequency and low-frequency components of the original image in the same frequency band in the spatial domain, thus preserving the identity information of the image while destroying as little stylistic information of the image as possible. We conduct extensive experiments on MRI images and natural images with FDDT and several mainstream baseline models, and we use four evaluation metrics to assess the quality of the generated images. Compared with the baseline models, optimally, FDDT can reduce Fr\'echet inception distance by up to 24.4%, structural similarity by up to 4.4%, peak signal-to-noise ratio by up to 5.8%, and mean squared error by up to 31%. Compared with the previous method, optimally, FDDT can reduce Fr\'echet inception distance by up to 23.7%, structural similarity by up to 1.8%, peak signal-to-noise ratio by up to 6.8%, and mean squared error by up to 31.6%.
Recently, Google proposes DDVM which for the first time demonstrates that a general diffusion model for image-to-image translation task works impressively well on optical flow estimation task without any specific designs like RAFT. However, DDVM is still a closed-source model with the expensive and private Palette-style pretraining. In this technical report, we present the first open-source DDVM by reproducing it. We study several design choices and find those important ones. By training on 40k public data with 4 GPUs, our reproduction achieves comparable performance to the closed-source DDVM. The code and model have been released in https://github.com/DQiaole/FlowDiffusion_pytorch.
This paper considers the out-of-distribution (OOD) generalization problem under the setting that both style distribution shift and spurious features exist and domain labels are missing. This setting frequently arises in real-world applications and is underlooked because previous approaches mainly handle either of these two factors. The critical challenge is decoupling style and spurious features in the absence of domain labels. To address this challenge, we first propose a structural causal model (SCM) for the image generation process, which captures both style distribution shift and spurious features. The proposed SCM enables us to design a new framework called IRSS, which can gradually separate style distribution and spurious features from images by introducing adversarial neural networks and multi-environment optimization, thus achieving OOD generalization. Moreover, it does not require additional supervision (e.g., domain labels) other than the images and their corresponding labels. Experiments on benchmark datasets demonstrate that IRSS outperforms traditional OOD methods and solves the problem of Invariant risk minimization (IRM) degradation, enabling the extraction of invariant features under distribution shift.