Dermatologists often diagnose or rule out early melanoma by evaluating the follow-up dermoscopic images of skin lesions. However, existing algorithms for early melanoma diagnosis are developed using single time-point images of lesions. Ignoring the temporal, morphological changes of lesions can lead to misdiagnosis in borderline cases. In this study, we propose a framework for automated early melanoma diagnosis using sequential dermoscopic images. To this end, we construct our method in three steps. First, we align sequential dermoscopic images of skin lesions using estimated Euclidean transformations, extract the lesion growth region by computing image differences among the consecutive images, and then propose a spatio-temporal network to capture the dermoscopic changes from aligned lesion images and the corresponding difference images. Finally, we develop an early diagnosis module to compute probability scores of malignancy for lesion images over time. We collected 179 serial dermoscopic imaging data from 122 patients to verify our method. Extensive experiments show that the proposed model outperforms other commonly used sequence models. We also compared the diagnostic results of our model with those of seven experienced dermatologists and five registrars. Our model achieved higher diagnostic accuracy than clinicians (63.69% vs. 54.33%, respectively) and provided an earlier diagnosis of melanoma (60.7% vs. 32.7% of melanoma correctly diagnosed on the first follow-up images). These results demonstrate that our model can be used to identify melanocytic lesions that are at high-risk of malignant transformation earlier in the disease process and thereby redefine what is possible in the early detection of melanoma.
Automatic evaluations for natural language generation (NLG) conventionally rely on token-level or embedding-level comparisons with the text references. This is different from human language processing, for which visual imaginations often improve comprehension. In this work, we propose ImaginE, an imagination-based automatic evaluation metric for natural language generation. With the help of CLIP and DALL-E, two cross-modal models pre-trained on large-scale image-text pairs, we automatically generate an image as the embodied imagination for the text snippet and compute the imagination similarity using contextual embeddings. Experiments spanning several text generation tasks demonstrate that adding imagination with our ImaginE displays great potential in introducing multi-modal information into NLG evaluation, and improves existing automatic metrics' correlations with human similarity judgments in many circumstances.
Numerous methods have been proposed to transform color and grayscale images to their single bit-per-pixel binary counterparts. Commonly, the goal is to enhance specific attributes of the original image to make it more amenable for analysis. However, when the resulting binarized image is intended for human viewing, aesthetics must also be considered. Binarization techniques, such as half-toning, stippling, and hatching, have been widely used for modeling the original image's intensity profile. We present an automated method to transform an image to a set of binary textures that represent not only the intensities, but also the colors of the original. The foundation of our method is information preservation: creating a set of textures that allows for the reconstruction of the original image's colors solely from the binarized representation. We present techniques to ensure that the textures created are not visually distracting, preserve the intensity profile of the images, and are natural in that they map sets of colors that are perceptually similar to patterns that are similar. The approach uses deep-neural networks and is entirely self-supervised; no examples of good vs. bad binarizations are required. The system yields aesthetically pleasing binary images when tested on a variety of image sources.
Generative adversarial networks (GANs) are one of the most widely used generative models. GANs can learn complex multi-modal distributions, and generate real-like samples. Despite the major success of GANs in generating synthetic data, they might suffer from unstable training process, and mode collapse. In this paper, we introduce a new GAN architecture called variance enforcing GAN (VARGAN), which incorporates a third network to introduce diversity in the generated samples. The third network measures the diversity of the generated samples, which is used to penalize the generator's loss for low diversity samples. The network is trained on the available training data and undesired distributions with limited modality. On a set of synthetic and real-world image data, VARGAN generates a more diverse set of samples compared to the recent state-of-the-art models. High diversity and low computational complexity, as well as fast convergence, make VARGAN a promising model to alleviate mode collapse.
Recently (Elkin, Filtser, Neiman 2017) introduced the concept of a {\it terminal embedding} from one metric space $(X,d_X)$ to another $(Y,d_Y)$ with a set of designated terminals $T\subset X$. Such an embedding $f$ is said to have distortion $\rho\ge 1$ if $\rho$ is the smallest value such that there exists a constant $C>0$ satisfying \begin{equation*} \forall x\in T\ \forall q\in X,\ C d_X(x, q) \le d_Y(f(x), f(q)) \le C \rho d_X(x, q) . \end{equation*} In the case that $X,Y$ are both Euclidean metrics with $Y$ being $m$-dimensional, recently (Narayanan, Nelson 2019), following work of (Mahabadi, Makarychev, Makarychev, Razenshteyn 2018), showed that distortion $1+\epsilon$ is achievable via such a terminal embedding with $m = O(\epsilon^{-2}\log n)$ for $n := |T|$. This generalizes the Johnson-Lindenstrauss lemma, which only preserves distances within $T$ and not to $T$ from the rest of space. The downside is that evaluating the embedding on some $q\in \mathbb{R}^d$ required solving a semidefinite program with $\Theta(n)$ constraints in $m$ variables and thus required some superlinear $\mathrm{poly}(n)$ runtime. Our main contribution in this work is to give a new data structure for computing terminal embeddings. We show how to pre-process $T$ to obtain an almost linear-space data structure that supports computing the terminal embedding image of any $q\in\mathbb{R}^d$ in sublinear time $n^{1-\Theta(\epsilon^2)+o(1)} + dn^{o(1)}$. To accomplish this, we leverage tools developed in the context of approximate nearest neighbor search.
Spiking neural networks (SNNs) can be run on neuromorphic devices with ultra-high speed and ultra-low energy consumption because of their binary and event-driven nature. Therefore, SNNs are expected to have various applications, including as generative models being running on edge devices to create high-quality images. In this study, we build a variational autoencoder (VAE) with SNN to enable image generation. VAE is known for its stability among generative models; recently, its quality advanced. In vanilla VAE, the latent space is represented as a normal distribution, and floating-point calculations are required in sampling. However, this is not possible in SNNs because all features must be binary time series data. Therefore, we constructed the latent space with an autoregressive SNN model, and randomly selected samples from its output to sample the latent variables. This allows the latent variables to follow the Bernoulli process and allows variational learning. Thus, we build the Fully Spiking Variational Autoencoder where all modules are constructed with SNN. To the best of our knowledge, we are the first to build a VAE only with SNN layers. We experimented with several datasets, and confirmed that it can generate images with the same or better quality compared to conventional ANNs. The code will be available soon.
The application of light field data in salient object de-tection is becoming increasingly popular recently. The diffi-culty lies in how to effectively fuse the features within the fo-cal stack and how to cooperate them with the feature of theall-focus image. Previous methods usually fuse focal stackfeatures via convolution or ConvLSTM, which are both lesseffective and ill-posed. In this paper, we model the infor-mation fusion within focal stack via graph networks. Theyintroduce powerful context propagation from neighbouringnodes and also avoid ill-posed implementations. On the onehand, we construct local graph connections thus avoidingprohibitive computational costs of traditional graph net-works. On the other hand, instead of processing the twokinds of data separately, we build a novel dual graph modelto guide the focal stack fusion process using all-focus pat-terns. To handle the second difficulty, previous methods usu-ally implement one-shot fusion for focal stack and all-focusfeatures, hence lacking a thorough exploration of their sup-plements. We introduce a reciprocative guidance schemeand enable mutual guidance between these two kinds of in-formation at multiple steps. As such, both kinds of featurescan be enhanced iteratively, finally benefiting the saliencyprediction. Extensive experimental results show that theproposed models are all beneficial and we achieve signif-icantly better results than state-of-the-art methods.
Deep person generation has attracted extensive research attention due to its wide applications in virtual agents, video conferencing, online shopping and art/movie production. With the advancement of deep learning, visual appearances (face, pose, cloth) of a person image can be easily generated or manipulated on demand. In this survey, we first summarize the scope of person generation, and then systematically review recent progress and technical trends in deep person generation, covering three major tasks: talking-head generation (face), pose-guided person generation (pose) and garment-oriented person generation (cloth). More than two hundred papers are covered for a thorough overview, and the milestone works are highlighted to witness the major technical breakthrough. Based on these fundamental tasks, a number of applications are investigated, e.g., virtual fitting, digital human, generative data augmentation. We hope this survey could shed some light on the future prospects of deep person generation, and provide a helpful foundation for full applications towards digital human.
In this paper we predict a full 3D avatar of a person from a single image. We infer texture and geometry in the UV-space of the SMPL model using an image-to-image translation method. Given partial texture and segmentation layout maps derived from the input view, our model predicts the complete segmentation map, the complete texture map, and a displacement map. The predicted maps can be applied to the SMPL model in order to naturally generalize to novel poses, shapes, and even new clothing. In order to learn our model in a common UV-space, we non-rigidly register the SMPL model to thousands of 3D scans, effectively encoding textures and geometries as images in correspondence. This turns a difficult 3D inference task into a simpler image-to-image translation one. Results on rendered scans of people and images from the DeepFashion dataset demonstrate that our method can reconstruct plausible 3D avatars from a single image. We further use our model to digitally change pose, shape, swap garments between people and edit clothing. To encourage research in this direction we will make the source code available for research purpose.
This paper presents a proof of concept for the usefulness of second-order texture features for the qualitative analysis and classification of chromogenic in-situ hybridization whole slide images in high-throughput imaging experiments. The challenge is that currently, the gold standard for gene expression grading in such images is expert assessment. The idea of the research team is to use different approaches in the analysis of these images that will be used for structural segmentation and functional analysis in gene expression. The article presents such perspective idea to select a number of textural features that are going to be used for classification. In our experiment, natural grouping of image samples (tiles) depending on their local texture properties was explored in an unsupervised classification procedure. The features are reduced to two dimensions with fuzzy c-means clustering. The overall conclusion of this experiment is that Haralick features are a viable choice for classification and analysis of chromogenic in-situ hybridization image data. The principal component analysis approach produced slightly more "understandable" from an annotator's point of view classes.