Computational cytology is a critical, rapid-developing, yet challenging topic in the field of medical image computing which analyzes the digitized cytology image by computer-aided technologies for cancer screening. Recently, an increasing number of deep learning (DL) algorithms have made significant progress in medical image analysis, leading to the boosting publications of cytological studies. To investigate the advanced methods and comprehensive applications, we survey more than 120 publications of DL-based cytology image analysis in this article. We first introduce various deep learning methods, including fully supervised, weakly supervised, unsupervised, and transfer learning. Then, we systematically summarize the public datasets, evaluation metrics, versatile cytology image analysis applications including classification, detection, segmentation, and other related tasks. Finally, we discuss current challenges and potential research directions of computational cytology.
Anomalies can be defined as any non-random structure which deviates from normality. Anomaly detection methods reported in the literature are numerous and diverse, as what is considered anomalous usually varies depending on particular scenarios and applications. In this work we propose an a contrario framework to detect anomalies in images applying statistical analysis to feature maps obtained via convolutions. We evaluate filters learned from the image under analysis via patch PCA, Gabor filters and the feature maps obtained from a pre-trained deep neural network (Resnet). The proposed method is multi-scale and fully unsupervised and is able to detect anomalies in a wide variety of scenarios. While the end goal of this work is the detection of subtle defects in leather samples for the automotive industry, we show that the same algorithm achieves state of the art results in public anomalies datasets.
The ability to discover new transients via image differencing without direct human intervention is an important task in observational astronomy. For these kind of image classification problems, machine Learning techniques such as Convolutional Neural Networks (CNNs) have shown remarkable success. In this work, we present the results of an automated transient identification on images with CNNs for an extant dataset from the Dark Energy Survey Supernova program (DES-SN), whose main focus was on using Type Ia supernovae for cosmology. By performing an architecture search of CNNs, we identify networks that efficiently select non-artifacts (e.g. supernovae, variable stars, AGN, etc.) from artifacts (image defects, mis-subtractions, etc.), achieving the efficiency of previous work performed with random Forests, without the need to expend any effort in feature identification. The CNNs also help us identify a subset of mislabeled images. Performing a relabeling of the images in this subset, the resulting classification with CNNs is significantly better than previous results.
We tackle the challenge of Visual Question Answering in multi-image setting for the ISVQA dataset. Traditional VQA tasks have focused on a single-image setting where the target answer is generated from a single image. Image set VQA, however, comprises of a set of images and requires finding connection between images, relate the objects across images based on these connections and generate a unified answer. In this report, we work with 4 approaches in a bid to improve the performance on the task. We analyse and compare our results with three baseline models - LXMERT, HME-VideoQA and VisualBERT - and show that our approaches can provide a slight improvement over the baselines. In specific, we try to improve on the spatial awareness of the model and help the model identify color using enhanced pre-training, reduce language dependence using adversarial regularization, and improve counting using regression loss and graph based deduplication. We further delve into an in-depth analysis on the language bias in the ISVQA dataset and show how models trained on ISVQA implicitly learn to associate language more strongly with the final answer.
Self-supervised learning on large-scale Vision Transformers (ViTs) as pre-training methods has achieved promising downstream performance. Yet, how such pre-training paradigms promote lightweight ViTs' performance is considerably less studied. In this work, we mainly produce recipes for pre-training high-performance lightweight ViTs using masked-image-modeling-based MAE, namely MAE-lite, which achieves 78.4% top-1 accuracy on ImageNet with ViT-Tiny (5.7M). Furthermore, we develop and benchmark other fully-supervised and self-supervised pre-training counterparts, e.g., contrastive-learning-based MoCo-v3, on both ImageNet and other classification tasks. We analyze and clearly show the effect of such pre-training, and reveal that properly-learned lower layers of the pre-trained models matter more than higher ones in data-sufficient downstream tasks. Finally, by further comparing with the pre-trained representations of the up-scaled models, a distillation strategy during pre-training is developed to improve the pre-trained representations as well, leading to further downstream performance improvement. The code and models will be made publicly available.
Deep learning-based single image deraining (SID) with unpaired information is of immense importance, as relying on paired synthetic data often limits their generality and scalability in real-world applications. However, we noticed that direct employ of unpaired adversarial learning and cycle-consistency constraints in the SID task is insufficient to learn the underlying relationship from rainy input to clean outputs, since the domain knowledge between rainy and rain-free images is asymmetrical. To address such limitation, we develop an effective unpaired SID method which explores mutual properties of the unpaired exemplars by a contrastive learning manner in a GAN framework, named as CDR-GAN. The proposed method mainly consists of two cooperative branches: Bidirectional Translation Branch (BTB) and Contrastive Guidance Branch (CGB). Specifically, BTB takes full advantage of the circulatory architecture of adversarial consistency to exploit latent feature distributions and guide transfer ability between two domains by equipping it with bidirectional mapping. Simultaneously, CGB implicitly constrains the embeddings of different exemplars in rain space by encouraging the similar feature distributions closer while pushing the dissimilar further away, in order to better help rain removal and image restoration. During training, we explore several loss functions to further constrain the proposed CDR-GAN. Extensive experiments show that our method performs favorably against existing unpaired deraining approaches on both synthetic and real-world datasets, even outperforms several fully-supervised or semi-supervised models.
The extensive use of medical CT has raised a public concern over the radiation dose to the patient. Reducing the radiation dose leads to increased CT image noise and artifacts, which can adversely affect not only the radiologists judgement but also the performance of downstream medical image analysis tasks. Various low-dose CT denoising methods, especially the recent deep learning based approaches, have produced impressive results. However, the existing denoising methods are all downstream-task-agnostic and neglect the diverse needs of the downstream applications. In this paper, we introduce a novel Task-Oriented Denoising Network (TOD-Net) with a task-oriented loss leveraging knowledge from the downstream tasks. Comprehensive empirical analysis shows that the task-oriented loss complements other task agnostic losses by steering the denoiser to enhance the image quality in the task related regions of interest. Such enhancement in turn brings general boosts on the performance of various methods for the downstream task. The presented work may shed light on the future development of context-aware image denoising methods.
Brain extraction is one of the first steps of pre-processing 3D brain MRI data. It is a prerequisite for any forthcoming brain imaging analyses. However, it is not a simple segmentation problem due to the complex structure of the brain and human head. Although multiple solutions have been proposed in the literature, we are still far from having truly robust methods. While previous methods have used machine learning with structural/geometric priors, with the development of deep learning in computer vision tasks, there has been an increase in proposed convolutional neural network architectures for this semantic segmentation task. Yet, most models focus on improving the training data and loss functions with little change in the architecture. In this paper, we propose a novel architecture we call EVC-Net. EVC-Net adds lower scale inputs on each encoder block. This enhances the multi-scale scheme of the V-Net architecture, hence increasing the efficiency of the model. Conditional Random Fields, a popular approach for image segmentation before the deep learning era, are re-introduced here as an additional step for refining the network's output to capture fine-grained results in segmentation. We compare our model to state-of-the-art methods such as HD-BET, Synthstrip and brainy. Results show that even with limited training resources, EVC-Net achieves higher Dice Coefficient and Jaccard Index along with lower surface distance.
Recently self-supervised representation learning has drawn considerable attention from the scene text recognition community. Different from previous studies using contrastive learning, we tackle the issue from an alternative perspective, i.e., by formulating the representation learning scheme in a generative manner. Typically, the neighboring image patches among one text line tend to have similar styles, including the strokes, textures, colors, etc. Motivated by this common sense, we augment one image patch and use its neighboring patch as guidance to recover itself. Specifically, we propose a Similarity-Aware Normalization (SimAN) module to identify the different patterns and align the corresponding styles from the guiding patch. In this way, the network gains representation capability for distinguishing complex patterns such as messy strokes and cluttered backgrounds. Experiments show that the proposed SimAN significantly improves the representation quality and achieves promising performance. Moreover, we surprisingly find that our self-supervised generative network has impressive potential for data synthesis, text image editing, and font interpolation, which suggests that the proposed SimAN has a wide range of practical applications.
This paper studies the task of conditional Human Motion Animation (cHMA). Given a source image and a driving video, the model should animate the new frame sequence, in which the person in the source image should perform a similar motion as the pose sequence from the driving video. Despite the success of Generative Adversarial Network (GANs) methods in image and video synthesis, it is still very challenging to conduct cHMA due to the difficulty in efficiently utilizing the conditional guided information such as images or poses, and generating images of good visual quality. To this end, this paper proposes a novel model of learning to Quantize, Scrabble, and Craft (QS-Craft) for conditional human motion animation. The key novelties come from the newly introduced three key steps: quantize, scrabble and craft. Particularly, our QS-Craft employs transformer in its structure to utilize the attention architectures. The guided information is represented as a pose coordinate sequence extracted from the driving videos. Extensive experiments on human motion datasets validate the efficacy of our model.