Out-of-distribution (OOD) generalisation aims to build a model that can well generalise its learnt knowledge from source domains to an unseen target domain. However, current image classification models often perform poorly in the OOD setting due to statistically spurious correlations learning from model training. From causality-based perspective, we formulate the data generation process in OOD image classification using a causal graph. On this graph, we show that prediction P(Y|X) of a label Y given an image X in statistical learning is formed by both causal effect P(Y|do(X)) and spurious effects caused by confounding features (e.g., background). Since the spurious features are domain-variant, the prediction P(Y|X) becomes unstable on unseen domains. In this paper, we propose to mitigate the spurious effect of confounders using front-door adjustment. In our method, the mediator variable is hypothesized as semantic features that are essential to determine a label for an image. Inspired by capability of style transfer in image generation, we interpret the combination of the mediator variable with different generated images in the front-door formula and propose novel algorithms to estimate it. Extensive experimental results on widely used benchmark datasets verify the effectiveness of our method.
Computer-aided pathology diagnosis based on the classification of Whole Slide Image (WSI) plays an important role in clinical practice, and it is often formulated as a weakly-supervised Multiple Instance Learning (MIL) problem. Existing methods solve this problem from either a bag classification or an instance classification perspective. In this paper, we propose an end-to-end weakly supervised knowledge distillation framework (WENO) for WSI classification, which integrates a bag classifier and an instance classifier in a knowledge distillation framework to mutually improve the performance of both classifiers. Specifically, an attention-based bag classifier is used as the teacher network, which is trained with weak bag labels, and an instance classifier is used as the student network, which is trained using the normalized attention scores obtained from the teacher network as soft pseudo labels for the instances in positive bags. An instance feature extractor is shared between the teacher and the student to further enhance the knowledge exchange between them. In addition, we propose a hard positive instance mining strategy based on the output of the student network to force the teacher network to keep mining hard positive instances. WENO is a plug-and-play framework that can be easily applied to any existing attention-based bag classification methods. Extensive experiments on five datasets demonstrate the efficiency of WENO. Code is available at https://github.com/miccaiif/WENO.
In deep active learning, it is especially important to choose multiple examples to markup at each step to work efficiently, especially on large datasets. At the same time, existing solutions to this problem in the Bayesian setup, such as BatchBALD, have significant limitations in selecting a large number of examples, associated with the exponential complexity of computing mutual information for joint random variables. We, therefore, present the Large BatchBALD algorithm, which gives a well-grounded approximation to the BatchBALD method that aims to achieve comparable quality while being more computationally efficient. We provide a complexity analysis of the algorithm, showing a reduction in computation time, especially for large batches. Furthermore, we present an extensive set of experimental results on image and text data, both on toy datasets and larger ones such as CIFAR-100.
Reference-based image super-resolution (RefSR) aims to exploit auxiliary reference (Ref) images to super-resolve low-resolution (LR) images. Recently, RefSR has been attracting great attention as it provides an alternative way to surpass single image SR. However, addressing the RefSR problem has two critical challenges: (i) It is difficult to match the correspondence between LR and Ref images when they are significantly different; (ii) How to transfer the relevant texture from Ref images to compensate the details for LR images is very challenging. To address these issues of RefSR, this paper proposes a deformable attention Transformer, namely DATSR, with multiple scales, each of which consists of a texture feature encoder (TFE) module, a reference-based deformable attention (RDA) module and a residual feature aggregation (RFA) module. Specifically, TFE first extracts image transformation (e.g., brightness) insensitive features for LR and Ref images, RDA then can exploit multiple relevant textures to compensate more information for LR features, and RFA lastly aggregates LR features and relevant textures to get a more visually pleasant result. Extensive experiments demonstrate that our DATSR achieves state-of-the-art performance on benchmark datasets quantitatively and qualitatively.
Score-based diffusion models have captured widespread attention and funded fast progress of recent vision generative tasks. In this paper, we focus on diffusion model backbone which has been much neglected before. We systematically explore vision Transformers as diffusion learners for various generative tasks. With our improvements the performance of vanilla ViT-based backbone (IU-ViT) is boosted to be on par with traditional U-Net-based methods. We further provide a hypothesis on the implication of disentangling the generative backbone as an encoder-decoder structure and show proof-of-concept experiments verifying the effectiveness of a stronger encoder for generative tasks with ASymmetriC ENcoder Decoder (ASCEND). Our improvements achieve competitive results on CIFAR-10, CelebA, LSUN, CUB Bird and large-resolution text-to-image tasks. To the best of our knowledge, we are the first to successfully train a single diffusion model on text-to-image task beyond 64x64 resolution. We hope this will motivate people to rethink the modeling choices and the training pipelines for diffusion-based generative models.
Applying Machine learning to domains like Earth Sciences is impeded by the lack of labeled data, despite a large corpus of raw data available in such domains. For instance, training a wildfire classifier on satellite imagery requires curating a massive and diverse dataset, which is an expensive and time-consuming process that can span from weeks to months. Searching for relevant examples in over 40 petabytes of unlabelled data requires researchers to manually hunt for such images, much like finding a needle in a haystack. We present a no-code end-to-end pipeline, Curator, which dramatically minimizes the time taken to curate an exhaustive labeled dataset. Curator is able to search massive amounts of unlabelled data by combining self-supervision, scalable nearest neighbor search, and active learning to learn and differentiate image representations. The pipeline can also be readily applied to solve problems across different domains. Overall, the pipeline makes it practical for researchers to go from just one reference image to a comprehensive dataset in a diminutive span of time.
This paper presents five different statistical methods for ground scene prediction (GSP) in wavelength-resolution synthetic aperture radar (SAR) images. The GSP image can be used as a reference image in a change detection algorithm yielding a high probability of detection and low false alarm rate. The predictions are based on image stacks, which are composed of images from the same scene acquired at different instants with the same flight geometry. The considered methods for obtaining the ground scene prediction include (i) autoregressive models; (ii) trimmed mean; (iii) median; (iv) intensity mean; and (v) mean. It is expected that the predicted image presents the true ground scene without change and preserves the ground backscattering pattern. The study indicate that the the median method provided the most accurate representation of the true ground. To show the applicability of the GSP, a change detection algorithm was considered using the median ground scene as a reference image. As a result, the median method displayed the probability of detection of $97\%$ and a false alarm rate of 0.11/km$^2, when considering military vehicles concealed in a forest.
In recent years, research on super-resolution has primarily focused on the development of unsupervised models, blind networks, and the use of optimization methods in non-blind models. But, limited research has discussed the loss function in the super-resolution process. The majority of those studies have only used perceptual similarity in a conventional way. This is while the development of appropriate loss can improve the quality of other methods as well. In this article, a new weighting method for pixel-wise loss is proposed. With the help of this method, it is possible to use trainable weights based on the general structure of the image and its perceptual features while maintaining the advantages of pixel-wise loss. Also, a criterion for comparing weights of loss is introduced so that the weights can be estimated directly by a convolutional neural network using this criterion. In addition, in this article, the expectation-maximization method is used for the simultaneous estimation super-resolution network and weighting network. In addition, a new activation function, called "FixedSum", is introduced which can keep the sum of all components of vector constants while keeping the output components between zero and one. As shown in the experimental results section, weighted loss by the proposed method leads to better results than the unweighted loss in both signal-to-noise and perceptual similarity senses.
Medical image segmentation is a fundamental and critical step in many image-guided clinical approaches. Recent success of deep learning-based segmentation methods usually relies on a large amount of labeled data, which is particularly difficult and costly to obtain especially in the medical imaging domain where only experts can provide reliable and accurate annotations. Semi-supervised learning has emerged as an appealing strategy and been widely applied to medical image segmentation tasks to train deep models with limited annotations. In this paper, we present a comprehensive review of recently proposed semi-supervised learning methods for medical image segmentation and summarized both the technical novelties and empirical results. Furthermore, we analyze and discuss the limitations and several unsolved problems of existing approaches. We hope this review could inspire the research community to explore solutions for this challenge and further promote the developments in medical image segmentation field.
Image registration is a key task in medical imaging applications, allowing to represent medical images in a common spatial reference frame. Current literature on image registration is generally based on the assumption that images are usually accessible to the researcher, from which the spatial transformation is subsequently estimated. This common assumption may not be met in current practical applications, since the sensitive nature of medical images may ultimately require their analysis under privacy constraints, preventing to share the image content in clear form. In this work, we formulate the problem of image registration under a privacy preserving regime, where images are assumed to be confidential and cannot be disclosed in clear. We derive our privacy preserving image registration framework by extending classical registration paradigms to account for advanced cryptographic tools, such as secure multi-party computation and homomorphic encryption, that enable the execution of operations without leaking the underlying data. To overcome the problem of performance and scalability of cryptographic tools in high dimensions, we first propose to optimize the underlying image registration operations using gradient approximations. We further revisit the use of homomorphic encryption and use a packing method to allow the encryption and multiplication of large matrices more efficiently. We demonstrate our privacy preserving framework in linear and non-linear registration problems, evaluating its accuracy and scalability with respect to standard image registration. Our results show that privacy preserving image registration is feasible and can be adopted in sensitive medical imaging applications.