WiTUnet: A U-Shaped Architecture Integrating CNN and Transformer for Improved Feature Alignment and Local Information Fusion

Low-dose computed tomography (LDCT) has become the technology of choice for diagnostic medical imaging, given its lower radiation dose compared to standard CT, despite increasing image noise and potentially affecting diagnostic accuracy. To address this, advanced deep learning-based LDCT denoising algorithms have been developed, primarily using Convolutional Neural Networks (CNNs) or Transformer Networks with the Unet architecture. This architecture enhances image detail by integrating feature maps from the encoder and decoder via skip connections. However, current methods often overlook enhancements to the Unet architecture itself, focusing instead on optimizing encoder and decoder structures. This approach can be problematic due to the significant differences in feature map characteristics between the encoder and decoder, where simple fusion strategies may not effectively reconstruct images.In this paper, we introduce WiTUnet, a novel LDCT image denoising method that utilizes nested, dense skip pathways instead of traditional skip connections to improve feature integration. WiTUnet also incorporates a windowed Transformer structure to process images in smaller, non-overlapping segments, reducing computational load. Additionally, the integration of a Local Image Perception Enhancement (LiPe) module in both the encoder and decoder replaces the standard multi-layer perceptron (MLP) in Transformers, enhancing local feature capture and representation. Through extensive experimental comparisons, WiTUnet has demonstrated superior performance over existing methods in key metrics such as Peak Signal-to-Noise Ratio (PSNR), Structural Similarity (SSIM), and Root Mean Square Error (RMSE), significantly improving noise removal and image quality.

3D-COCO: extension of MS-COCO dataset for image detection and 3D reconstruction modules

We introduce 3D-COCO, an extension of the original MS-COCO dataset providing 3D models and 2D-3D alignment annotations. 3D-COCO was designed to achieve computer vision tasks such as 3D reconstruction or image detection configurable with textual, 2D image, and 3D CAD model queries. We complete the existing MS-COCO dataset with 28K 3D models collected on ShapeNet and Objaverse. By using an IoU-based method, we match each MS-COCO annotation with the best 3D models to provide a 2D-3D alignment. The open-source nature of 3D-COCO is a premiere that should pave the way for new research on 3D-related topics. The dataset and its source codes is available at https://kalisteo.cea.fr/index.php/coco3d-object-detection-and-reconstruction/

Deformable MRI Sequence Registration for AI-based Prostate Cancer Diagnosis

The PI-CAI (Prostate Imaging: Cancer AI) challenge led to expert-level diagnostic algorithms for clinically significant prostate cancer detection. The algorithms receive biparametric MRI scans as input, which consist of T2-weighted and diffusion-weighted scans. These scans can be misaligned due to multiple factors in the scanning process. Image registration can alleviate this issue by predicting the deformation between the sequences. We investigate the effect of image registration on the diagnostic performance of AI-based prostate cancer diagnosis. First, the image registration algorithm, developed in MeVisLab, is analyzed using a dataset with paired lesion annotations. Second, the effect on diagnosis is evaluated by comparing case-level cancer diagnosis performance between using the original dataset, rigidly aligned diffusion-weighted scans, or deformably aligned diffusion-weighted scans. Rigid registration showed no improvement. Deformable registration demonstrated a substantial improvement in lesion overlap (+10% median Dice score) and a positive yet non-significant improvement in diagnostic performance (+0.3% AUROC, p=0.18). Our investigation shows that a substantial improvement in lesion alignment does not directly lead to a significant improvement in diagnostic performance. Qualitative analysis indicated that jointly developing image registration methods and diagnostic AI algorithms could enhance diagnostic accuracy and patient outcomes.

Mixed-Query Transformer: A Unified Image Segmentation Architecture

Existing unified image segmentation models either employ a unified architecture across multiple tasks but use separate weights tailored to each dataset, or apply a single set of weights to multiple datasets but are limited to a single task. In this paper, we introduce the Mixed-Query Transformer (MQ-Former), a unified architecture for multi-task and multi-dataset image segmentation using a single set of weights. To enable this, we propose a mixed query strategy, which can effectively and dynamically accommodate different types of objects without heuristic designs. In addition, the unified architecture allows us to use data augmentation with synthetic masks and captions to further improve model generalization. Experiments demonstrate that MQ-Former can not only effectively handle multiple segmentation datasets and tasks compared to specialized state-of-the-art models with competitive performance, but also generalize better to open-set segmentation tasks, evidenced by over 7 points higher performance than the prior art on the open-vocabulary SeginW benchmark.

Reference-Based 3D-Aware Image Editing with Triplane

Generative Adversarial Networks (GANs) have emerged as powerful tools not only for high-quality image generation but also for real image editing through manipulation of their interpretable latent spaces. Recent advancements in GANs include the development of 3D-aware models such as EG3D, characterized by efficient triplane-based architectures enabling the reconstruction of 3D geometry from single images. However, scant attention has been devoted to providing an integrated framework for high-quality reference-based 3D-aware image editing within this domain. This study addresses this gap by exploring and demonstrating the effectiveness of EG3D's triplane space for achieving advanced reference-based edits, presenting a unique perspective on 3D-aware image editing through our novel pipeline. Our approach integrates the encoding of triplane features, spatial disentanglement and automatic localization of features in the triplane domain, and fusion learning for desired image editing. Moreover, our framework demonstrates versatility across domains, extending its effectiveness to animal face edits and partial stylization of cartoon portraits. The method shows significant improvements over relevant 3D-aware latent editing and 2D reference-based editing methods, both qualitatively and quantitatively. Project page: https://three-bee.github.io/triplane_edit

Do LLMs Understand Visual Anomalies? Uncovering LLM Capabilities in Zero-shot Anomaly Detection

Large vision-language models (LVLMs) are markedly proficient in deriving visual representations guided by natural language. Recent explorations have utilized LVLMs to tackle zero-shot visual anomaly detection (VAD) challenges by pairing images with textual descriptions indicative of normal and abnormal conditions, referred to as anomaly prompts. However, existing approaches depend on static anomaly prompts that are prone to cross-semantic ambiguity, and prioritize global image-level representations over crucial local pixel-level image-to-text alignment that is necessary for accurate anomaly localization. In this paper, we present ALFA, a training-free approach designed to address these challenges via a unified model. We propose a run-time prompt adaptation strategy, which first generates informative anomaly prompts to leverage the capabilities of a large language model (LLM). This strategy is enhanced by a contextual scoring mechanism for per-image anomaly prompt adaptation and cross-semantic ambiguity mitigation. We further introduce a novel fine-grained aligner to fuse local pixel-level semantics for precise anomaly localization, by projecting the image-text alignment from global to local semantic spaces. Extensive evaluations on the challenging MVTec and VisA datasets confirm ALFA's effectiveness in harnessing the language potential for zero-shot VAD, achieving significant PRO improvements of 12.1% on MVTec AD and 8.9% on VisA compared to state-of-the-art zero-shot VAD approaches.

Concept Weaver: Enabling Multi-Concept Fusion in Text-to-Image Models

While there has been significant progress in customizing text-to-image generation models, generating images that combine multiple personalized concepts remains challenging. In this work, we introduce Concept Weaver, a method for composing customized text-to-image diffusion models at inference time. Specifically, the method breaks the process into two steps: creating a template image aligned with the semantics of input prompts, and then personalizing the template using a concept fusion strategy. The fusion strategy incorporates the appearance of the target concepts into the template image while retaining its structural details. The results indicate that our method can generate multiple custom concepts with higher identity fidelity compared to alternative approaches. Furthermore, the method is shown to seamlessly handle more than two concepts and closely follow the semantic meaning of the input prompt without blending appearances across different subjects.

FPL+: Filtered Pseudo Label-based Unsupervised Cross-Modality Adaptation for 3D Medical Image Segmentation

Adapting a medical image segmentation model to a new domain is important for improving its cross-domain transferability, and due to the expensive annotation process, Unsupervised Domain Adaptation (UDA) is appealing where only unlabeled images are needed for the adaptation. Existing UDA methods are mainly based on image or feature alignment with adversarial training for regularization, and they are limited by insufficient supervision in the target domain. In this paper, we propose an enhanced Filtered Pseudo Label (FPL+)-based UDA method for 3D medical image segmentation. It first uses cross-domain data augmentation to translate labeled images in the source domain to a dual-domain training set consisting of a pseudo source-domain set and a pseudo target-domain set. To leverage the dual-domain augmented images to train a pseudo label generator, domain-specific batch normalization layers are used to deal with the domain shift while learning the domain-invariant structure features, generating high-quality pseudo labels for target-domain images. We then combine labeled source-domain images and target-domain images with pseudo labels to train a final segmentor, where image-level weighting based on uncertainty estimation and pixel-level weighting based on dual-domain consensus are proposed to mitigate the adverse effect of noisy pseudo labels. Experiments on three public multi-modal datasets for Vestibular Schwannoma, brain tumor and whole heart segmentation show that our method surpassed ten state-of-the-art UDA methods, and it even achieved better results than fully supervised learning in the target domain in some cases.

Bootstrapping Chest CT Image Understanding by Distilling Knowledge from X-ray Expert Models

Radiologists highly desire fully automated versatile AI for medical imaging interpretation. However, the lack of extensively annotated large-scale multi-disease datasets has hindered the achievement of this goal. In this paper, we explore the feasibility of leveraging language as a naturally high-quality supervision for chest CT imaging. In light of the limited availability of image-report pairs, we bootstrap the understanding of 3D chest CT images by distilling chest-related diagnostic knowledge from an extensively pre-trained 2D X-ray expert model. Specifically, we propose a language-guided retrieval method to match each 3D CT image with its semantically closest 2D X-ray image, and perform pair-wise and semantic relation knowledge distillation. Subsequently, we use contrastive learning to align images and reports within the same patient while distinguishing them from the other patients. However, the challenge arises when patients have similar semantic diagnoses, such as healthy patients, potentially confusing if treated as negatives. We introduce a robust contrastive learning that identifies and corrects these false negatives. We train our model with over 12,000 pairs of chest CT images and radiology reports. Extensive experiments across multiple scenarios, including zero-shot learning, report generation, and fine-tuning processes, demonstrate the model's feasibility in interpreting chest CT images.

Coreset Selection for Object Detection

Coreset selection is a method for selecting a small, representative subset of an entire dataset. It has been primarily researched in image classification, assuming there is only one object per image. However, coreset selection for object detection is more challenging as an image can contain multiple objects. As a result, much research has yet to be done on this topic. Therefore, we introduce a new approach, Coreset Selection for Object Detection (CSOD). CSOD generates imagewise and classwise representative feature vectors for multiple objects of the same class within each image. Subsequently, we adopt submodular optimization for considering both representativeness and diversity and utilize the representative vectors in the submodular optimization process to select a subset. When we evaluated CSOD on the Pascal VOC dataset, CSOD outperformed random selection by +6.4%p in AP$_{50}$ when selecting 200 images.