Ambitions for the next generation of wireless communication include high data rates, low latency, ubiquitous access, ensuring sustainability (in terms of consumption of energy and natural resources), all while maintaining a reasonable level of implementation complexity. Achieving these goals necessitates reforms in cellular networks, specifically in the physical layer and antenna design. The deployment of transmissive metasurfaces at basestations (BSs) presents an appealing solution, enabling beamforming in the radiated wave domain, minimizing the need for energy-hungry RF chains. Among various metasurface-based antenna designs, we propose using Huygens' metasurface-based antennas (HMAs) at BSs. Huygens' metasurfaces offer an attractive solution for antennas because, by utilizing Huygens' equivalence principle, they allow independent control over both the amplitude and phase of the transmitted electromagnetic wave. In this paper, we investigate the fundamental limits of HMAs in wireless networks by integrating electromagnetic theory and information theory within a unified analytical framework. Specifically, we model the unique electromagnetic characteristics of HMAs and incorporate them into an information-theoretic optimization framework to determine their maximum achievable sum rate. By formulating an optimization problem that captures the impact of HMA's hardware constraints and electromagnetic properties, we quantify the channel capacity of HMA-assisted systems. We then compare the performance of HMAs against phased arrays and other metasurface-based antennas in both rich scattering and realistic 3GPP channels, highlighting their potential in improving spectral and energy efficiency.