Dual self-distillation of U-shaped networks for 3D medical image segmentation

U-shaped networks and its variants have demonstrated exceptional results for medical image segmentation. In this paper, we propose a novel dual self-distillation (DSD) framework for U-shaped networks for 3D medical image segmentation. DSD distills knowledge from the ground-truth segmentation labels to the decoder layers and also between the encoder and decoder layers of a single U-shaped network. DSD is a generalized training strategy that could be attached to the backbone architecture of any U-shaped network to further improve its segmentation performance. We attached DSD on two state-of-the-art U-shaped backbones, and extensive experiments on two public 3D medical image segmentation datasets (cardiac substructure and brain tumor) demonstrated significant improvement over those backbones. On average, after attaching DSD to the U-shaped backbones, we observed an improvement of 4.25% and 3.15% in Dice similarity score for cardiac substructure and brain tumor segmentation respectively.