Weakly supervised multiple instance learning histopathological tumor segmentation

Histopathological image segmentation is a challenging and important topic in medical imaging with tremendous potential impact in clinical practice. State of the art methods relying on hand-crafted annotations that reduce the scope of the solutions since digital histology suffers from standardization and samples differ significantly between cancer phenotypes. To this end, in this paper, we propose a weakly supervised framework relying on weak standard clinical practice annotations, available in most medical centers. In particular, we exploit a multiple instance learning scheme providing a label for each instance, establishing a detailed segmentation of whole slide images. The potential of the framework is assessed with multi-centric data experiments using The Cancer Genome Atlas repository and the publicly available PatchCamelyon dataset. Promising results when compared with experts' annotations demonstrate the potentials of our approach.

Learning to run a power network challenge for training topology controllers

For power grid operations, a large body of research focuses on using generation redispatching, load shedding or demand side management flexibilities. However, a less costly and potentially more flexible option would be grid topology reconfiguration, as already partially exploited by Coreso (European RSC) and RTE (French TSO) operations. Beyond previous work on branch switching, bus reconfigurations are a broader class of action and could provide some substantial benefits to route electricity and optimize the grid capacity to keep it within safety margins. Because of its non-linear and combinatorial nature, no existing optimal power flow solver can yet tackle this problem. We here propose a new framework to learn topology controllers through imitation and reinforcement learning. We present the design and the results of the first "Learning to Run a Power Network" challenge released with this framework. We finally develop a method providing performance upper-bounds (oracle), which highlights remaining unsolved challenges and suggests future directions of improvement.