Sora is the first large-scale generalist video generation model that garnered significant attention across society. Since its launch by OpenAI in February 2024, no other video generation models have paralleled {Sora}'s performance or its capacity to support a broad spectrum of video generation tasks. Additionally, there are only a few fully published video generation models, with the majority being closed-source. To address this gap, this paper proposes a new multi-agent framework Mora, which incorporates several advanced visual AI agents to replicate generalist video generation demonstrated by Sora. In particular, Mora can utilize multiple visual agents and successfully mimic Sora's video generation capabilities in various tasks, such as (1) text-to-video generation, (2) text-conditional image-to-video generation, (3) extend generated videos, (4) video-to-video editing, (5) connect videos and (6) simulate digital worlds. Our extensive experimental results show that Mora achieves performance that is proximate to that of Sora in various tasks. However, there exists an obvious performance gap between our work and Sora when assessed holistically. In summary, we hope this project can guide the future trajectory of video generation through collaborative AI agents.
With the rapid growth of artificial intelligence (AI) in healthcare, there has been a significant increase in the generation and storage of sensitive medical data. This abundance of data, in turn, has propelled the advancement of medical AI technologies. However, concerns about unauthorized data exploitation, such as training commercial AI models, often deter researchers from making their invaluable datasets publicly available. In response to the need to protect this hard-to-collect data while still encouraging medical institutions to share it, one promising solution is to introduce imperceptible noise into the data. This method aims to safeguard the data against unauthorized training by inducing degradation in model generalization. Although existing methods have shown commendable data protection capabilities in general domains, they tend to fall short when applied to biomedical data, mainly due to their failure to account for the sparse nature of medical images. To address this problem, we propose the Sparsity-Aware Local Masking (SALM) method, a novel approach that selectively perturbs significant pixel regions rather than the entire image as previous strategies have done. This simple-yet-effective approach significantly reduces the perturbation search space by concentrating on local regions, thereby improving both the efficiency and effectiveness of data protection for biomedical datasets characterized by sparse features. Besides, we have demonstrated that SALM maintains the essential characteristics of the data, ensuring its clinical utility remains uncompromised. Our extensive experiments across various datasets and model architectures demonstrate that SALM effectively prevents unauthorized training of deep-learning models and outperforms previous state-of-the-art data protection methods.
Alzheimer's Disease (AD) is a neurodegenerative condition characterized by diverse progression rates among individuals, with changes in cortical thickness (CTh) closely linked to its progression. Accurately forecasting CTh trajectories can significantly enhance early diagnosis and intervention strategies, providing timely care. However, the longitudinal data essential for these studies often suffer from temporal sparsity and incompleteness, presenting substantial challenges in modeling the disease's progression accurately. Existing methods are limited, focusing primarily on datasets without missing entries or requiring predefined assumptions about CTh progression. To overcome these obstacles, we propose a conditional score-based diffusion model specifically designed to generate CTh trajectories with the given baseline information, such as age, sex, and initial diagnosis. Our conditional diffusion model utilizes all available data during the training phase to make predictions based solely on baseline information during inference without needing prior history about CTh progression. The prediction accuracy of the proposed CTh prediction pipeline using a conditional score-based model was compared for sub-groups consisting of cognitively normal, mild cognitive impairment, and AD subjects. The Bland-Altman analysis shows our diffusion-based prediction model has a near-zero bias with narrow 95% confidential interval compared to the ground-truth CTh in 6-36 months. In addition, our conditional diffusion model has a stochastic generative nature, therefore, we demonstrated an uncertainty analysis of patient-specific CTh prediction through multiple realizations.
Data scarcity and privacy concerns limit the availability of high-quality medical images for public use, which can be mitigated through medical image synthesis. However, current medical image synthesis methods often struggle to accurately capture the complexity of detailed anatomical structures and pathological conditions. To address these challenges, we propose a novel medical image synthesis model that leverages fine-grained image-text alignment and anatomy-pathology prompts to generate highly detailed and accurate synthetic medical images. Our method integrates advanced natural language processing techniques with image generative modeling, enabling precise alignment between descriptive text prompts and the synthesized images' anatomical and pathological details. The proposed approach consists of two key components: an anatomy-pathology prompting module and a fine-grained alignment-based synthesis module. The anatomy-pathology prompting module automatically generates descriptive prompts for high-quality medical images. To further synthesize high-quality medical images from the generated prompts, the fine-grained alignment-based synthesis module pre-defines a visual codebook for the radiology dataset and performs fine-grained alignment between the codebook and generated prompts to obtain key patches as visual clues, facilitating accurate image synthesis. We validate the superiority of our method through experiments on public chest X-ray datasets and demonstrate that our synthetic images preserve accurate semantic information, making them valuable for various medical applications.
Sora is a text-to-video generative AI model, released by OpenAI in February 2024. The model is trained to generate videos of realistic or imaginative scenes from text instructions and show potential in simulating the physical world. Based on public technical reports and reverse engineering, this paper presents a comprehensive review of the model's background, related technologies, applications, remaining challenges, and future directions of text-to-video AI models. We first trace Sora's development and investigate the underlying technologies used to build this "world simulator". Then, we describe in detail the applications and potential impact of Sora in multiple industries ranging from film-making and education to marketing. We discuss the main challenges and limitations that need to be addressed to widely deploy Sora, such as ensuring safe and unbiased video generation. Lastly, we discuss the future development of Sora and video generation models in general, and how advancements in the field could enable new ways of human-AI interaction, boosting productivity and creativity of video generation.
As Large Language Models (LLMs) are integrated into critical real-world applications, their strategic and logical reasoning abilities are increasingly crucial. This paper evaluates LLMs' reasoning abilities in competitive environments through game-theoretic tasks, e.g., board and card games that require pure logic and strategic reasoning to compete with opponents. We first propose GTBench, a language-driven environment composing 10 widely-recognized tasks, across a comprehensive game taxonomy: complete versus incomplete information, dynamic versus static, and probabilistic versus deterministic scenarios. Then, we investigate two key problems: (1) Characterizing game-theoretic reasoning of LLMs; (2) LLM-vs-LLM competitions as reasoning evaluation. We observe that (1) LLMs have distinct behaviors regarding various gaming scenarios; for example, LLMs fail in complete and deterministic games yet they are competitive in probabilistic gaming scenarios; (2) Open-source LLMs, e.g., CodeLlama-34b-Instruct, are less competitive than commercial LLMs, e.g., GPT-4, in complex games. In addition, code-pretraining greatly benefits strategic reasoning, while advanced reasoning methods such as Chain-of-Thought (CoT) and Tree-of-Thought (ToT) do not always help. Detailed error profiles are also provided for a better understanding of LLMs' behavior.
The development of large vision-language models (LVLMs) offers the potential to address challenges faced by traditional multimodal recommendations thanks to their proficient understanding of static images and textual dynamics. However, the application of LVLMs in this field is still limited due to the following complexities: First, LVLMs lack user preference knowledge as they are trained from vast general datasets. Second, LVLMs suffer setbacks in addressing multiple image dynamics in scenarios involving discrete, noisy, and redundant image sequences. To overcome these issues, we propose the novel reasoning scheme named Rec-GPT4V: Visual-Summary Thought (VST) of leveraging large vision-language models for multimodal recommendation. We utilize user history as in-context user preferences to address the first challenge. Next, we prompt LVLMs to generate item image summaries and utilize image comprehension in natural language space combined with item titles to query the user preferences over candidate items. We conduct comprehensive experiments across four datasets with three LVLMs: GPT4-V, LLaVa-7b, and LLaVa-13b. The numerical results indicate the efficacy of VST.
Multimodal Large Language Models (MLLMs) have gained significant attention recently, showing remarkable potential in artificial general intelligence. However, assessing the utility of MLLMs presents considerable challenges, primarily due to the absence multimodal benchmarks that align with human preferences. Inspired by LLM-as-a-Judge in LLMs, this paper introduces a novel benchmark, termed MLLM-as-a-Judge, to assess the ability of MLLMs in assisting judges including three distinct tasks: Scoring Evaluation, Pair Comparison, and Batch Ranking. Our study reveals that, while MLLMs demonstrate remarkable human-like discernment in Pair Comparisons, there is a significant divergence from human preferences in Scoring Evaluation and Batch Ranking tasks. Furthermore, MLLMs still face challenges in judgment, including diverse biases, hallucinatory responses, and inconsistencies, even for advanced models such as GPT-4V. These findings emphasize the pressing need for enhancements and further research efforts regarding MLLMs as fully reliable evaluators. Code and dataset are available at https://github.com/Dongping-Chen/MLLM-as-a-Judge.
Do large language models (LLMs) exhibit any forms of awareness similar to humans? In this paper, we introduce the concept of awareness to LLMs, arguing that awareness is an essential aspect of trustworthiness for LLMs to enhance their interaction with humans while ensuring ethical responses. We define awareness in LLMs as the ability to perceive and understand themselves as AI models and to exhibit social intelligence. We identify four key dimensions of awareness: capability, mission, emotion, and perspective. To assess LLMs on these dimensions, we introduce a specialized dataset, AwareLLM dataset. Our findings reveal that LLMs demonstrate a decent degree of awareness, though they still lack substantial capability awareness.
Collaborative learning (CL) is a distributed learning framework that aims to protect user privacy by allowing users to jointly train a model by sharing their gradient updates only. However, gradient inversion attacks (GIAs), which recover users' training data from shared gradients, impose severe privacy threats to CL. Existing defense methods adopt different techniques, e.g., differential privacy, cryptography, and perturbation defenses, to defend against the GIAs. Nevertheless, all current defense methods suffer from a poor trade-off between privacy, utility, and efficiency. To mitigate the weaknesses of existing solutions, we propose a novel defense method, Dual Gradient Pruning (DGP), based on gradient pruning, which can improve communication efficiency while preserving the utility and privacy of CL. Specifically, DGP slightly changes gradient pruning with a stronger privacy guarantee. And DGP can also significantly improve communication efficiency with a theoretical analysis of its convergence and generalization. Our extensive experiments show that DGP can effectively defend against the most powerful GIAs and reduce the communication cost without sacrificing the model's utility.