The adversarial risk of a machine learning model has been widely studied. Most previous works assume that the data lies in the whole ambient space. We propose to take a new angle and take the manifold assumption into consideration. Assuming data lies in a manifold, we investigate two new types of adversarial risk, the normal adversarial risk due to perturbation along normal direction, and the in-manifold adversarial risk due to perturbation within the manifold. We prove that the classic adversarial risk can be bounded from both sides using the normal and in-manifold adversarial risks. We also show with a surprisingly pessimistic case that the standard adversarial risk can be nonzero even when both normal and in-manifold risks are zero. We finalize the paper with empirical studies supporting our theoretical results. Our results suggest the possibility of improving the robustness of a classifier by only focusing on the normal adversarial risk.
Optical flow estimation is a fundamental task in computer vision. Recent direct-regression methods using deep neural networks achieve remarkable performance improvement. However, they do not explicitly capture long-term motion correspondences and thus cannot handle large motions effectively. In this paper, inspired by the traditional matching-optimization methods where matching is introduced to handle large displacements before energy-based optimizations, we introduce a simple but effective global matching step before the direct regression and develop a learning-based matching-optimization framework, namely GMFlowNet. In GMFlowNet, global matching is efficiently calculated by applying argmax on 4D cost volumes. Additionally, to improve the matching quality, we propose patch-based overlapping attention to extract large context features. Extensive experiments demonstrate that GMFlowNet outperforms RAFT, the most popular optimization-only method, by a large margin and achieves state-of-the-art performance on standard benchmarks. Thanks to the matching and overlapping attention, GMFlowNet obtains major improvements on the predictions for textureless regions and large motions. Our code is made publicly available at https://github.com/xiaofeng94/GMFlowNet
Combining information from multi-view images is crucial to improve the performance and robustness of automated methods for disease diagnosis. However, due to the non-alignment characteristics of multi-view images, building correlation and data fusion across views largely remain an open problem. In this study, we present TransFusion, a Transformer-based architecture to merge divergent multi-view imaging information using convolutional layers and powerful attention mechanisms. In particular, the Divergent Fusion Attention (DiFA) module is proposed for rich cross-view context modeling and semantic dependency mining, addressing the critical issue of capturing long-range correlations between unaligned data from different image views. We further propose the Multi-Scale Attention (MSA) to collect global correspondence of multi-scale feature representations. We evaluate TransFusion on the Multi-Disease, Multi-View \& Multi-Center Right Ventricular Segmentation in Cardiac MRI (M\&Ms-2) challenge cohort. TransFusion demonstrates leading performance against the state-of-the-art methods and opens up new perspectives for multi-view imaging integration towards robust medical image segmentation.
Top-down instance segmentation framework has shown its superiority in object detection compared to the bottom-up framework. While it is efficient in addressing over-segmentation, top-down instance segmentation suffers from over-crop problem. However, a complete segmentation mask is crucial for biological image analysis as it delivers important morphological properties such as shapes and volumes. In this paper, we propose a region proposal rectification (RPR) module to address this challenging incomplete segmentation problem. In particular, we offer a progressive ROIAlign module to introduce neighbor information into a series of ROIs gradually. The ROI features are fed into an attentive feed-forward network (FFN) for proposal box regression. With additional neighbor information, the proposed RPR module shows significant improvement in correction of region proposal locations and thereby exhibits favorable instance segmentation performances on three biological image datasets compared to state-of-the-art baseline methods. Experimental results demonstrate that the proposed RPR module is effective in both anchor-based and anchor-free top-down instance segmentation approaches, suggesting the proposed method can be applied to general top-down instance segmentation of biological images.
Most methods for conditional video synthesis use a single modality as the condition. This comes with major limitations. For example, it is problematic for a model conditioned on an image to generate a specific motion trajectory desired by the user since there is no means to provide motion information. Conversely, language information can describe the desired motion, while not precisely defining the content of the video. This work presents a multimodal video generation framework that benefits from text and images provided jointly or separately. We leverage the recent progress in quantized representations for videos and apply a bidirectional transformer with multiple modalities as inputs to predict a discrete video representation. To improve video quality and consistency, we propose a new video token trained with self-learning and an improved mask-prediction algorithm for sampling video tokens. We introduce text augmentation to improve the robustness of the textual representation and diversity of generated videos. Our framework can incorporate various visual modalities, such as segmentation masks, drawings, and partially occluded images. It can generate much longer sequences than the one used for training. In addition, our model can extract visual information as suggested by the text prompt, e.g., "an object in image one is moving northeast", and generate corresponding videos. We run evaluations on three public datasets and a newly collected dataset labeled with facial attributes, achieving state-of-the-art generation results on all four.
Transformers have emerged to be successful in a number of natural language processing and vision tasks, but their potential applications to medical imaging remain largely unexplored due to the unique difficulties of this field. In this study, we present UTNetV2, a simple yet powerful backbone model that combines the strengths of the convolutional neural network and Transformer for enhancing performance and efficiency in medical image segmentation. The critical design of UTNetV2 includes three innovations: (1) We used a hybrid hierarchical architecture by introducing depthwise separable convolution to projection and feed-forward network in the Transformer block, which brings local relationship modeling and desirable properties of CNNs (translation invariance) to Transformer, thus eliminate the requirement of large-scale pre-training. (2) We proposed efficient bidirectional attention (B-MHA) that reduces the quadratic computation complexity of self-attention to linear by introducing an adaptively updated semantic map. The efficient attention makes it possible to capture long-range relationship and correct the fine-grained errors in high-resolution token maps. (3) The semantic maps in the B-MHA allow us to perform semantically and spatially global multi-scale feature fusion without introducing much computational overhead. Furthermore, we provide a fair comparison codebase of CNN-based and Transformer-based on various medical image segmentation tasks to evaluate the merits and defects of both architectures. UTNetV2 demonstrated state-of-the-art performance across various settings, including large-scale datasets, small-scale datasets, 2D and 3D settings.
Multi-modality images have been widely used and provide comprehensive information for medical image analysis. However, acquiring all modalities among all institutes is costly and often impossible in clinical settings. To leverage more comprehensive multi-modality information, we propose a privacy secured decentralized multi-modality adaptive learning architecture named ModalityBank. Our method could learn a set of effective domain-specific modulation parameters plugged into a common domain-agnostic network. We demonstrate by switching different sets of configurations, the generator could output high-quality images for a specific modality. Our method could also complete the missing modalities across all data centers, thus could be used for modality completion purposes. The downstream task trained from the synthesized multi-modality samples could achieve higher performance than learning from one real data center and achieve close-to-real performance compare with all real images.
Medical image segmentation has been widely recognized as a pivot procedure for clinical diagnosis, analysis, and treatment planning. However, the laborious and expensive annotation process lags down the speed of further advances. Contrastive learning-based weight pre-training provides an alternative by leveraging unlabeled data to learn a good representation. In this paper, we investigate how contrastive learning benefits the general supervised medical segmentation tasks. To this end, patch-dragsaw contrastive regularization (PDCR) is proposed to perform patch-level tugging and repulsing with the extent controlled by a continuous affinity score. And a new structure dubbed uncertainty-aware feature selection block (UAFS) is designed to perform the feature selection process, which can handle the learning target shift caused by minority features with high uncertainty. By plugging the proposed 2 modules into the existing segmentation architecture, we achieve state-of-the-art results across 8 public datasets from 6 domains. Newly designed modules further decrease the amount of training data to a quarter while achieving comparable, if not better, performances. From this perspective, we take the opposite direction of the original self/un-supervised contrastive learning by further excavating information contained within the label.
The American Sign Language Linguistic Research Project (ASLLRP) provides Internet access to high-quality ASL video data, generally including front and side views and a close-up of the face. The manual and non-manual components of the signing have been linguistically annotated using SignStream(R). The recently expanded video corpora can be browsed and searched through the Data Access Interface (DAI 2) we have designed; it is possible to carry out complex searches. The data from our corpora can also be downloaded; annotations are available in an XML export format. We have also developed the ASLLRP Sign Bank, which contains almost 6,000 sign entries for lexical signs, with distinct English-based glosses, with a total of 41,830 examples of lexical signs (in addition to about 300 gestures, over 1,000 fingerspelled signs, and 475 classifier examples). The Sign Bank is likewise accessible and searchable on the Internet; it can also be accessed from within SignStream(R) (software to facilitate linguistic annotation and analysis of visual language data) to make annotations more accurate and efficient. Here we describe the available resources. These data have been used for many types of research in linguistics and in computer-based sign language recognition from video; examples of such research are provided in the latter part of this article.
StyleGANs have shown impressive results on data generation and manipulation in recent years, thanks to its disentangled style latent space. A lot of efforts have been made in inverting a pretrained generator, where an encoder is trained ad hoc after the generator is trained in a two-stage fashion. In this paper, we focus on style-based generators asking a scientific question: Does forcing such a generator to reconstruct real data lead to more disentangled latent space and make the inversion process from image to latent space easy? We describe a new methodology to train a style-based autoencoder where the encoder and generator are optimized end-to-end. We show that our proposed model consistently outperforms baselines in terms of image inversion and generation quality. Supplementary, code, and pretrained models are available on the project website.