Self-attention (SA) mechanisms have been widely used in developing sequential recommendation (SR) methods, and demonstrated state-of-the-art performance. However, in this paper, we show that self-attentive SR methods substantially suffer from the over-smoothing issue that item embeddings within a sequence become increasingly similar across attention blocks. As widely demonstrated in the literature, this issue could lead to a loss of information in individual items, and significantly degrade models' scalability and performance. To address the over-smoothing issue, in this paper, we view items within a sequence constituting a star graph and develop a method, denoted as MSSG, for SR. Different from existing self-attentive methods, MSSG introduces an additional internal node to specifically capture the global information within the sequence, and does not require information propagation among items. This design fundamentally addresses the over-smoothing issue and enables MSSG a linear time complexity with respect to the sequence length. We compare MSSG with ten state-of-the-art baseline methods on six public benchmark datasets. Our experimental results demonstrate that MSSG significantly outperforms the baseline methods, with an improvement of as much as 10.10%. Our analysis shows the superior scalability of MSSG over the state-of-the-art self-attentive methods. Our complexity analysis and run-time performance comparison together show that MSSG is both theoretically and practically more efficient than self-attentive methods. Our analysis of the attention weights learned in SA-based methods indicates that on sparse recommendation data, modeling dependencies in all item pairs using the SA mechanism yields limited information gain, and thus, might not benefit the recommendation performance
Recently, drug repurposing has emerged as an effective and resource-efficient paradigm for AD drug discovery. Among various methods for drug repurposing, network-based methods have shown promising results as they are capable of leveraging complex networks that integrate multiple interaction types, such as protein-protein interactions, to more effectively identify candidate drugs. However, existing approaches typically assume paths of the same length in the network have equal importance in identifying the therapeutic effect of drugs. Other domains have found that same length paths do not necessarily have the same importance. Thus, relying on this assumption may be deleterious to drug repurposing attempts. In this work, we propose MPI (Modeling Path Importance), a novel network-based method for AD drug repurposing. MPI is unique in that it prioritizes important paths via learned node embeddings, which can effectively capture a network's rich structural information. Thus, leveraging learned embeddings allows MPI to effectively differentiate the importance among paths. We evaluate MPI against a commonly used baseline method that identifies anti-AD drug candidates primarily based on the shortest paths between drugs and AD in the network. We observe that among the top-50 ranked drugs, MPI prioritizes 20.0% more drugs with anti-AD evidence compared to the baseline. Finally, Cox proportional-hazard models produced from insurance claims data aid us in identifying the use of etodolac, nicotine, and BBB-crossing ACE-INHs as having a reduced risk of AD, suggesting such drugs may be viable candidates for repurposing and should be explored further in future studies.
The two-hand interaction is one of the most challenging signals to analyze due to the self-similarity, complicated articulations, and occlusions of hands. Although several datasets have been proposed for the two-hand interaction analysis, all of them do not achieve 1) diverse and realistic image appearances and 2) diverse and large-scale groundtruth (GT) 3D poses at the same time. In this work, we propose Re:InterHand, a dataset of relighted 3D interacting hands that achieve the two goals. To this end, we employ a state-of-the-art hand relighting network with our accurately tracked two-hand 3D poses. We compare our Re:InterHand with existing 3D interacting hands datasets and show the benefit of it. Our Re:InterHand is available in https://mks0601.github.io/ReInterHand/.
Text-guided image editing faces significant challenges to training and inference flexibility. Much literature collects large amounts of annotated image-text pairs to train text-conditioned generative models from scratch, which is expensive and not efficient. After that, some approaches that leverage pre-trained vision-language models are put forward to avoid data collection, but they are also limited by either per text-prompt optimization or inference-time hyper-parameters tuning. To address these issues, we investigate and identify a specific space, referred to as CLIP DeltaSpace, where the CLIP visual feature difference of two images is semantically aligned with the CLIP textual feature difference of their corresponding text descriptions. Based on DeltaSpace, we propose a novel framework called DeltaEdit, which maps the CLIP visual feature differences to the latent space directions of a generative model during the training phase, and predicts the latent space directions from the CLIP textual feature differences during the inference phase. And this design endows DeltaEdit with two advantages: (1) text-free training; (2) generalization to various text prompts for zero-shot inference. Extensive experiments validate the effectiveness and versatility of DeltaEdit with different generative models, including both the GAN model and the diffusion model, in achieving flexible text-guided image editing. Code is available at https://github.com/Yueming6568/DeltaEdit.
Recent works have successfully extended large-scale text-to-image models to the video domain, producing promising results but at a high computational cost and requiring a large amount of video data. In this work, we introduce ConditionVideo, a training-free approach to text-to-video generation based on the provided condition, video, and input text, by leveraging the power of off-the-shelf text-to-image generation methods (e.g., Stable Diffusion). ConditionVideo generates realistic dynamic videos from random noise or given scene videos. Our method explicitly disentangles the motion representation into condition-guided and scenery motion components. To this end, the ConditionVideo model is designed with a UNet branch and a control branch. To improve temporal coherence, we introduce sparse bi-directional spatial-temporal attention (sBiST-Attn). The 3D control network extends the conventional 2D controlnet model, aiming to strengthen conditional generation accuracy by additionally leveraging the bi-directional frames in the temporal domain. Our method exhibits superior performance in terms of frame consistency, clip score, and conditional accuracy, outperforming other compared methods.
In recent years, with large language models (LLMs) achieving state-of-the-art performance in context understanding, increasing efforts have been dedicated to developing LLM-enhanced sequential recommendation (SR) methods. Considering that most existing LLMs are not specifically optimized for recommendation tasks, adapting them for SR becomes a critical step in LLM-enhanced SR methods. Though numerous adaptation methods have been developed, it still remains a significant challenge to adapt LLMs for SR both efficiently and effectively. To address this challenge, in this paper, we introduce a novel side sequential network adaptation method, denoted as SSNA, for LLM enhanced SR. SSNA features three key designs to allow both efficient and effective LLM adaptation. First, SSNA learns adapters separate from LLMs, while fixing all the pre-trained parameters within LLMs to allow efficient adaptation. In addition, SSNA adapts the top-a layers of LLMs jointly, and integrates adapters sequentially for enhanced effectiveness (i.e., recommendation performance). We compare SSNA against five state-of-the-art baseline methods on five benchmark datasets using three LLMs. The experimental results demonstrate that SSNA significantly outperforms all the baseline methods in terms of recommendation performance, and achieves substantial improvement over the best-performing baseline methods at both run-time and memory efficiency during training. Our analysis shows the effectiveness of integrating adapters in a sequential manner. Our parameter study demonstrates the effectiveness of jointly adapting the top-a layers of LLMs.
Currently, existing efforts in Weakly Supervised Semantic Segmentation (WSSS) based on Convolutional Neural Networks (CNNs) have predominantly focused on enhancing the multi-label classification network stage, with limited attention given to the equally important downstream segmentation network. Furthermore, CNN-based local convolutions lack the ability to model the extensive inter-category dependencies. Therefore, this paper introduces a graph reasoning-based approach to enhance WSSS. The aim is to improve WSSS holistically by simultaneously enhancing both the multi-label classification and segmentation network stages. In the multi-label classification network segment, external knowledge is integrated, coupled with GCNs, to globally reason about inter-class dependencies. This encourages the network to uncover features in non-salient regions of images, thereby refining the completeness of generated pseudo-labels. In the segmentation network segment, the proposed Graph Reasoning Mapping (GRM) module is employed to leverage knowledge obtained from textual databases, facilitating contextual reasoning for class representation within image regions. This GRM module enhances feature representation in high-level semantics of the segmentation network's local convolutions, while dynamically learning semantic coherence for individual samples. Using solely image-level supervision, we have achieved state-of-the-art performance in WSSS on the PASCAL VOC 2012 and MS-COCO datasets. Extensive experimentation on both the multi-label classification and segmentation network stages underscores the effectiveness of the proposed graph reasoning approach for advancing WSSS.
Recently, advancements in deep learning-based superpixel segmentation methods have brought about improvements in both the efficiency and the performance of segmentation. However, a significant challenge remains in generating superpixels that strictly adhere to object boundaries while conveying rich visual significance, especially when cross-surface color correlations may interfere with objects. Drawing inspiration from neural structure and visual mechanisms, we propose a biological network architecture comprising an Enhanced Screening Module (ESM) and a novel Boundary-Aware Label (BAL) for superpixel segmentation. The ESM enhances semantic information by simulating the interactive projection mechanisms of the visual cortex. Additionally, the BAL emulates the spatial frequency characteristics of visual cortical cells to facilitate the generation of superpixels with strong boundary adherence. We demonstrate the effectiveness of our approach through evaluations on both the BSDS500 dataset and the NYUv2 dataset.
Unsupervised skin lesion segmentation offers several benefits, including conserving expert human resources, reducing discrepancies due to subjective human labeling, and adapting to novel environments. However, segmenting dermoscopic images without manual labeling guidance presents significant challenges due to dermoscopic image artifacts such as hair noise, blister noise, and subtle edge differences. To address these challenges, we introduce an innovative Uncertainty Self-Learning Network (USL-Net) designed for skin lesion segmentation. The USL-Net can effectively segment a range of lesions, eliminating the need for manual labeling guidance. Initially, features are extracted using contrastive learning, followed by the generation of Class Activation Maps (CAMs) as saliency maps using these features. The different CAM locations correspond to the importance of the lesion region based on their saliency. High-saliency regions in the map serve as pseudo-labels for lesion regions while low-saliency regions represent the background. However, intermediate regions can be hard to classify, often due to their proximity to lesion edges or interference from hair or blisters. Rather than risk potential pseudo-labeling errors or learning confusion by forcefully classifying these regions, we consider them as uncertainty regions, exempting them from pseudo-labeling and allowing the network to self-learn. Further, we employ connectivity detection and centrality detection to refine foreground pseudo-labels and reduce noise-induced errors. The application of cycle refining enhances performance further. Our method underwent thorough experimental validation on the ISIC-2017, ISIC-2018, and PH2 datasets, demonstrating that its performance is on par with weakly supervised and supervised methods, and exceeds that of other existing unsupervised methods.